Effect of vitamin B12 supplementation on glycemic control in poorly controlled hyperhomocysteinemic type 2 diabetic patients
| العنوان: | Effect of vitamin B12 supplementation on glycemic control in poorly controlled hyperhomocysteinemic type 2 diabetic patients |
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| المؤلفون: | Yogendra Keche, Radha Yegnanarayan, Shreepad Bhat |
| المصدر: | Bangladesh Journal of Pharmacology, Vol 11, Iss 1, Pp 50-53 (2016) Bangladesh Journal of Pharmacology, Vol 11, Iss 1 (2015) |
| بيانات النشر: | Bangladesh Pharmacological Society, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Pharmacology, Vitamin b, medicine.medical_specialty, business.industry, Serum homocysteine, lcsh:RM1-950, Blood sugar, nutritional and metabolic diseases, Hyperhomocysteinemic, Hba1c level, Glycemic control, Endocrinology, Pharmacotherapy, lcsh:Therapeutics. Pharmacology, Vitamin B12 supplementation, Internal medicine, Methylcobalamin, medicine, Vitamin B12, Type 2 diabetic, business, medicine.drug, Glycemic |
| الوصف: | This study was conducted to observe the effect of vitamin B12 supplementation on glycemic control in poorly controlled hyperhomocysteinemic type 2 diabetic patients by measuring HbA1c levels at baseline and 4 weeks. Patient having serum homocysteine more than 15 µmol/L or vitamin B12 less than 223 pg/mL were enrolled in this study. One group received methylcobalamin 500 µg daily with their usual anti-diabetic therapy and the other group received only suitable anti-diabetic drug therapy. Methylcobalamin 500 µg was given daily for period of 4 weeks. Glycemic control was measured by levels of HbA1c, blood sugar at baseline and at 4 weeks. Serum homocysteine levels was reduced from 21.5 ± 2.6 to 15.4 ± 6.4 (p=0.04) with vitamin B12 supplementation at 4 weeks. At 4 weeks, HbA1c decreased from 9.9 ± 0.9 to 8.7 ± 0.5 (p12 deficient patients after vitamin B12 supplementation. There is role of vitamin B12 in glycemic control in poorly controlled type 2 diabetic patients. |
| اللغة: | English |
| تدمد: | 1991-0088 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8c6e9df8ea1f06f06619bb6b22e335 http://www.banglajol.info/bd/index.php/BJP/article/view/24141 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....3b8c6e9df8ea1f06f06619bb6b22e335 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19910088 |
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