Clinically established biodegradable long acting injectables: An industry perspective
العنوان: | Clinically established biodegradable long acting injectables: An industry perspective |
---|---|
المؤلفون: | Nkanga, Christian Isalomboto, Fisch, Andreas, Rad-Malekshahi, Mazda, Romic, Marieta Duvnjak, Kittel, Birgit, Ullrich, Thomas, Wang, Jing, Krause, Rui Werner Maçedo, Adler, Sabine, Lammers, Twan, Hennink, Wim E, Ramazani, Farshad, Afd Pharmaceutics, Pharmaceutics |
المساهمون: | Afd Pharmaceutics, Pharmaceutics |
المصدر: | Advanced Drug Delivery Reviews, 167, 19. Elsevier |
سنة النشر: | 2020 |
مصطلحات موضوعية: | Chemistry, Pharmaceutical, Oil-based formulations, Plga microparticles, Pharmaceutical Science, Nanotechnology, 02 engineering and technology, Drug crystals, PLGA microparticles, Microsphere, 03 medical and health sciences, Drug Delivery Systems, Polylactic Acid-Polyglycolic Acid Copolymer, Suspensions, Absorbable Implants, Drug crystal suspensions, Humans, Implants, 030304 developmental biology, Drug Implants, 0303 health sciences, 021001 nanoscience & nanotechnology, Microspheres, Drug Liberation, Extended release, Long acting, Delayed-Action Preparations, Drug delivery, Nanoparticles, Emulsions, In situ forming implants, Business, 0210 nano-technology, Long acting injectables |
الوصف: | Long acting injectable formulations have been developed to sustain the action of drugs in the body over desired periods of time. These delivery platforms have been utilized for both systemic and local drug delivery applications. This review gives an overview of long acting injectable systems that are currently in clinical use. These products are categorized in three different groups: biodegradable polymeric systems, including microparticles and implants; micro and nanocrystal suspensions and oil-based formulations. Furthermore, the applications of these drug delivery platforms for the management of various chronic diseases are summarized. Finally, this review addresses industrial challenges regarding the development of long acting injectable formulations. |
وصف الملف: | application/pdf |
اللغة: | English |
تدمد: | 0169-409X |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea773efedb65d6be73ed0d2e7f9afad https://dspace.library.uu.nl/handle/1874/411319 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....3ea773efedb65d6be73ed0d2e7f9afad |
قاعدة البيانات: | OpenAIRE |
كن أول من يترك تعليقا!