Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement

التفاصيل البيبلوغرافية
العنوان: Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement
المؤلفون: Jan-Peter Glossmann, Volker Diehl, Jan Oliver Staak, Andreas Josting, Claudia Wickenhauser
المصدر: Leukemialymphoma. 44(9)
سنة النشر: 2003
مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Cancer Research, Acute myelogenous leukemia (AML), Sialoglycoproteins, Myelogenous, Fatal Outcome, Antigens, CD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Testis, Biomarkers, Tumor, Medicine, Humans, Vimentin, Sarcoma, Myeloid, Thioguanine, Paresis, Aged, Cerebral Hemorrhage, Skin, Leukosialin, business.industry, Daunorubicin, Stomach, Cytarabine, Myeloid leukemia, Combination chemotherapy, Hematology, Exanthema, medicine.disease, Neoplasm Proteins, Leukemia, Oncology, Arm, Sarcoma, medicine.symptom, Mitoxantrone, business, Carboxylic Ester Hydrolases, medicine.drug
الوصف: Granulocytic sarcoma (extramedullary myelosarcoma, chloroma) is a rare extramedullary myeloid tumor which can occur at any anatomical site as isolated finding or associated with acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS). In this case, we describe a 71-year-old man who presented with incomplete paresis of the left arm, periorbital swelling, a maculopapular exanthema and organ involvement including testis and stomach. The tumors responded to combination chemotherapy and the patient fully recovered. However, after five months the patient relapsed and died quickly. This case confirms the importance of including granulocytic sarcoma in the differential diagnoses of a variety of diseases. In AML, the presence of granulocytic sarcoma is associated with worse overall survival. When diagnosed, it should be treated with intensive chemotherapy as soon as possible.
تدمد: 1042-8194
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46faeced2be8543a1c899d3cd5d3b006
https://pubmed.ncbi.nlm.nih.gov/14565668
رقم الأكسشن: edsair.doi.dedup.....46faeced2be8543a1c899d3cd5d3b006
قاعدة البيانات: OpenAIRE