أعرض في EDS

An improved brine shrimp larvae lethality microwell test method

التفاصيل البيبلوغرافية
العنوان: An improved brine shrimp larvae lethality microwell test method
المؤلفون: Jun Mu, Yi Zhang, Xiao-jie Gu, Jinyuan Han
المصدر: Toxicology Mechanisms and Methods. 22:23-30
بيانات النشر: Informa UK Limited, 2011.
سنة النشر: 2011
مصطلحات موضوعية: Photoperiod, Health, Toxicology and Mutagenesis, Artemia parthenogenetica, High density, Antineoplastic Agents, Brine shrimp, Toxicology, Sensitivity and Specificity, Median lethal dose, Lethal Dose 50, Metals, Heavy, Toxicity Tests, Animals, Pesticides, Larva, Chromatography, Dose-Response Relationship, Drug, biology, Reproducibility of Results, Heavy metals, Pesticide, biology.organism_classification, Survival Analysis, Environmental Pollutants, Lethality, Artemia
الوصف: This article described an improved brine shrimp larvae lethality microwell test method. A simply designed connecting vessel with alternative photoperiod was used to culture and collect high yield of active Artemia parthenogenetica nauplii for brine shrimp larvae lethality microwell test. Using this method, pure A. parthenogenetica nauplii suspension was easily cultured and harvested with high density about 100-150 larvae per milliliter and the natural mortality was reduced to near zero by elimination of unnecessary artificial disturbance. And its sensitivity was validated by determination of LC(50)-24 h of different reference toxicants including five antitumor agents, two pesticides, three organic pollutants, and four heavy metals salts, most of which exhibited LC(50)-24 h between 0.07 and 58.43 mg/L except for bleomycin and mitomycin C with LC(50)-24 h over 300 mg/L.
تدمد: 1537-6524
1537-6516
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485cd88bb4dd25781cc5bfbdbee4072d
https://doi.org/10.3109/15376516.2011.583297
رقم الأكسشن: edsair.doi.dedup.....485cd88bb4dd25781cc5bfbdbee4072d
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15376524
15376516