QLIF-05. A SINGLE INSTITUTION’S EXPERIENCE EXPLORING THE ASSOCIATION OF INTEGRATIVE MEDICINE AND SURVIVORSHIP IN GLIOBLASTOMA
| العنوان: | QLIF-05. A SINGLE INSTITUTION’S EXPERIENCE EXPLORING THE ASSOCIATION OF INTEGRATIVE MEDICINE AND SURVIVORSHIP IN GLIOBLASTOMA |
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| المؤلفون: | Frances McSherry, Patrick Healy, Henry S. Friedman, Dina Randazzo, Eric S. Lipp, James E. Herndon, Annick Desjardins, Mary Lou Affronti, Katherine B. Peters |
| المصدر: | Neuro-Oncology. 19:vi202-vi202 |
| بيانات النشر: | Oxford University Press (OUP), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Gerontology, Cancer Research, medicine.medical_specialty, animal structures, Standard of care, business.industry, Alternative medicine, medicine.disease, Abstracts, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Survivorship curve, Medicine, Neurology (clinical), Integrative medicine, Single institution, business, 030217 neurology & neurosurgery, Glioblastoma |
| الوصف: | Complementary and Alternative Medicine (CAM) uses diverse practices and products that are not a part of standard of care while Integrative Medicine combines both CAM and conventional medicine. Given the poor prognosis of glioblastoma (GBM), many patients will explore other options to improve survival or quality of life. We sought to examine the association between CAM modalities and survivorship. In this cross-sectional retrospective analysis, data about CAM treatment and self-help practices were obtained from the modified International Complementary and Alternative Medicine Questionnaire (I-CAM-Q). CAM treatment included modalities such as vitamins/supplements, massage, energy work, or acupuncture, while CAM self-help practices consisted of praying, exercise, visualization, meditation, relaxation, or diet. Survival was defined by date of questionnaire completion to date of death. There were 365 GBM patients (31% censored) with a median overall survival (mOS) of 14.1months, 95% CI: 12.2, 17.0. Those patients who used CAM self-help practices (n=188, mOS =16.2 months, 95% CI: 12.2, 18.1) and CAM treatments (n=237, mOS = 15.5 months, 95% CI: 9.9, 18.1) did not have any association with survival compared to those who did not use self-help (n=65; mOS = 20.9 months, 95% CI: 12.7, 39.1) or CAM treatments (n=74, mOS = 15.5 months, 95% CI: 9.9, 18.1). The most popular modalities used, prayer (n=171, 15.1 vs 22.7 months) and supplements (n=220; 14.7 vs 16.5 months) were also not associated with survival. The use of CAM was not a predictor of survival whereas those who were multifocal, grade IV, older than 55, or had recurrent disease had significantly poorer survival. It is difficult to accurately predict survival benefit because of this study’s cross-sectional design. Due to the increased interest in CAM in the primary brain tumor population, a prospective analysis utilizing some of these self- help practices or treatments may be warranted. |
| تدمد: | 1523-5866 1522-8517 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491d831bf3aeaa459c45e6271bee99c4 https://doi.org/10.1093/neuonc/nox168.816 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....491d831bf3aeaa459c45e6271bee99c4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15235866 15228517 |
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