Phorbol esters as probes of the regulation of thyrotropin secretion
| العنوان: | Phorbol esters as probes of the regulation of thyrotropin secretion |
|---|---|
| المؤلفون: | David Senator, Ronald J. Koenig, P. Reed Larsen |
| المصدر: | Biochemical and Biophysical Research Communications. 125:353-359 |
| بيانات النشر: | Elsevier BV, 1984. |
| سنة النشر: | 1984 |
| مصطلحات موضوعية: | Male, endocrine system, medicine.medical_specialty, endocrine system diseases, Biophysics, Thyrotropin, Thyrotropin-releasing hormone, Biochemistry, chemistry.chemical_compound, Pituitary Gland, Anterior, Thyrotropin-releasing hormone receptor, Internal medicine, Phorbol Esters, medicine, Protein biosynthesis, Pi, Animals, Phorbol esters, Secretion, Cycloheximide, Thyrotropin-Releasing Hormone, Molecular Biology, Calcimycin, Triiodothyronine, Dose-Response Relationship, Drug, Rats, Inbred Strains, Cell Biology, Phorbols, Rats, Endocrinology, chemistry, Phorbol, Tetradecanoylphorbol Acetate, hormones, hormone substitutes, and hormone antagonists |
| الوصف: | 12-0-Tetradecanoylphorbol 13-acetate and thyrotropin releasing hormone were compared as thyrotropin secretagogues in cultured rat pituitary cells. The maximal secretion evoked by the former was only half that evoked by the latter. A23187 plus 12-0-tetradecanoylphorbol 13-acetate together produced as large a response as thyrotropin releasing hormone. Triiodothyronine inhibited phorbol ester-induced thyrotropin secretion, and this inhibition required protein synthesis. |
| تدمد: | 0006-291X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da68eb7157701672e19d44a1842a659 https://doi.org/10.1016/s0006-291x(84)80375-7 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....4da68eb7157701672e19d44a1842a659 |
| قاعدة البيانات: | OpenAIRE |
كن أول من يترك تعليقا!