Spinal anesthesia: a comparison of procaine and lidocaine
العنوان: | Spinal anesthesia: a comparison of procaine and lidocaine |
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المؤلفون: | Lyne Bergeron, Michel Girard, Pierre Drolet, Carl Boucher, Yvan Grenier, Hong Hanh Le Truong |
المصدر: | Canadian Journal of Anesthesia. 48:470-473 |
بيانات النشر: | Springer Science and Business Media LLC, 2001. |
سنة النشر: | 2001 |
مصطلحات موضوعية: | Adult, Male, musculoskeletal diseases, medicine.medical_specialty, Time Factors, Lidocaine, medicine.drug_class, medicine.disease_cause, Anesthesia, Spinal, Procaine, Double-Blind Method, Anesthesiology, medicine, Humans, Prospective Studies, Anesthetics, Local, Sensory level, Local anesthetic, business.industry, Spinal anesthesia, General Medicine, musculoskeletal system, nervous system diseases, Surgery, stomatognathic diseases, Anesthesiology and Pain Medicine, Regional anesthesia, Anesthesia, Female, Irritation, business, medicine.drug |
الوصف: | To compare spinal procaine to spinal lidocaine with regard to their main clinical characteristics and incidence of transient radicular irritation (TRI).In this randomized, double-blind, prospective study, patients (two groups, n=30 each) received either 100 mg of lidocaine 5% in 7.5% glucose (Group L) or 100 mg of procaine 10% diluted with 1 ml cerebrospinal fluid (Group P). After spinal anesthesia, segmental level of sensory block was assessed by pinprick. Blood pressure and the height of the block were noted each minute for the first ten minutes, then every three minutes for the next 35 min and finally every five minutes until regression of the block to L4. Motor blockade was evaluated using the Bromage scale. To evaluate the presence of TRI, each patient was questioned 48 hr after surgery.Time to highest sensory level and to maximum number of segments blocked showed no difference between groups. Mean time for sensory regression to T10 and for regression of the motor block were shorter in Group P. Eighty minutes following injection, sensory levels were lower in Group P. Five patients had inadequate surgical anesthesia in Group P and only one in Group L. No patient in Group P had TRI (95% CI 10-12%) while eight (27%) in Group L did (95% CI 12-46%).Procaine 10% was associated with a clinical failure rate of 14.2%. This characteristic must be balanced against an absence of TRI, which occurs more frequently with the use of lidocaine 5%. |
تدمد: | 1496-8975 0832-610X |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db137beb3d8ad21684c7d837348251a https://doi.org/10.1007/bf03028311 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....4db137beb3d8ad21684c7d837348251a |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14968975 0832610X |
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