Loss of bacterial diversity in the sinuses is associated with lower smell discrimination scores
| العنوان: | Loss of bacterial diversity in the sinuses is associated with lower smell discrimination scores |
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| المؤلفون: | Charlotte Ballauf, Richard G. Douglas, Kristi Biswas, Julia Draf, Brett Wagner Mackenzie, Thomas Hummel |
| المصدر: | Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020) Scientific Reports |
| بيانات النشر: | Georg Thieme Verlag KG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Nasal cavity, Male, Meatus, Population, Anosmia, Physiology, lcsh:Medicine, Zoology, Olfaction, Biology, Microbiology, Article, 03 medical and health sciences, Olfaction Disorders, 0302 clinical medicine, Hyposmia, Respiratory signs and symptoms, RNA, Ribosomal, 16S, Paranasal Sinuses, medicine, Humans, Microbiome, 030223 otorhinolaryngology, education, lcsh:Science, Aged, education.field_of_study, Multidisciplinary, Bacteria, lcsh:R, Middle Aged, Smell, 030104 developmental biology, medicine.anatomical_structure, Sensory Thresholds, Female, lcsh:Q, medicine.symptom, Nasal Cavity, Olfactory epithelium, Diversity (business) |
| الوصف: | Olfactory impairment affects ~ 20% of the population and has been linked to various serious disorders. Microbes in the nasal cavity play a key role in priming the physiology of the olfactory epithelium and maintaining a normal sense of smell by the host. The aim of this study was to explore the link between olfactory dysfunction and nasal bacterial communities. A total of 162 subjects were recruited for this study from a specialized olfactory dysfunction clinic and placed into one of three groups: anosmia, hyposmia or normosmia. Swabs from the nasal middle meatus were collected from each subject then processed for bacterial 16S rRNA gene sequencing. No overall differences in bacterial diversity or composition were observed between the three cohorts in this study. However, the relative abundances of Corynebacterium spp. and Streptococcus spp. were significantly (p p |
| تدمد: | 1438-8685 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524ca7f3dc6e929ec6cb57cc5e9fd06c https://doi.org/10.1055/s-0041-1728855 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....524ca7f3dc6e929ec6cb57cc5e9fd06c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14388685 |
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