Ramadan and gestational diabetes: maternal and neonatal outcomes

التفاصيل البيبلوغرافية
العنوان: Ramadan and gestational diabetes: maternal and neonatal outcomes
المؤلفون: Margaret McGill, Anna Jane Harding, Christine Pech, Lynda Molyneaux, Maria I. Constantino, Glynis P. Ross, Abdullah A Alrasheed, Ted Wu, Turki Abdullah AlMogbel, Jencia Wong
المصدر: Acta Diabetologica
بيانات النشر: Springer Milan, 2021.
سنة النشر: 2021
مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Maternal, Outcomes, Third trimester, Teaching hospital, Fetal Macrosomia, Endocrinology, Pregnancy, Diabetes mellitus, Neonatal, Internal Medicine, medicine, Birth Weight, Humans, Gestational diabetes, Retrospective Studies, Ramadan, business.industry, Obstetrics, Infant, Newborn, Retrospective cohort study, General Medicine, medicine.disease, Hypoglycemia, Fasting Status, Diabetes, Gestational, Neonatal outcomes, Original Article, Female, business
الوصف: Aims The impact of Ramadan exposure to Gestational Diabetes Mellitus (GDM) pregnancies is not known. We therefore aimed to assess the association of Ramadan with maternal and neonatal outcomes among pregnant women with GDM. Methods Retrospective cohort study of 345 Muslim women with singleton pregnancies who attended a major Sydney teaching hospital during the period 1989–2010, was undertaken. Exposure to Ramadan was stratified by the: (1) total pregnancy days exposed to Ramadan, (2) duration (hours) of daily fasting and (3) trimester of exposure. Maternal and neonatal outcomes were examined by exposure status, and never exposed pregnancies were comparator in all three analyses. Fasting status was not recorded. Results We found no significant effect of Ramadan exposure on mean birthweight, macrosomia and maternal outcomes. However, we found a significant trend for increased neonatal hyperbilirubinemia with increasing Ramadan days exposure and later trimester exposure (ptrend ≤ 0.02 for both), with adjusted OR 3.9 (p=0.03) for those with ≥ 21 days exposure to Ramadan and adjusted OR 4.3 (p=0.04) for third trimester exposure. Conversely longer Ramadan exposure and late trimester exposure were independently associated with a lower prevalence of neonatal hypoglycaemia (adjusted OR 0.4 and 0.3 for ≥ 21 days and third trimester exposure, respectively). Furthermore, neonatal hypoglycaemia decreased for the fasting period of > 15 h group (adjusted OR 0.2, p = 0.01). Conclusions Ramadan exposure is associated with reduced neonatal hypoglycaemia, with no effect on birthweight, implying more favourable glycaemic control. However, the fourfold excess of neonatal hyperbilirubinemia indicates a need for further study of Ramadan and GDM.
اللغة: English
تدمد: 1432-5233
0940-5429
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e37b75d816b16f768dcc14df08e2271
http://europepmc.org/articles/PMC8758603
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....5e37b75d816b16f768dcc14df08e2271
قاعدة البيانات: OpenAIRE