Vitamin D and bone mineral status of newborn-maternal pair delivering at a tertiary hospital in Nigeria

التفاصيل البيبلوغرافية
العنوان: Vitamin D and bone mineral status of newborn-maternal pair delivering at a tertiary hospital in Nigeria
المؤلفون: HA Elechi, MA Alhaji, MB Faruk, HW Idris, AO Oduwole
المصدر: Nigerian journal of clinical practice. 24(3)
سنة النشر: 2021
مصطلحات موضوعية: Bone mineral, Pregnancy, Minerals, business.industry, Offspring, Albumin, Infant, Newborn, Physiology, Nigeria, General Medicine, medicine.disease, vitamin D deficiency, Elevated alkaline phosphatase, Tertiary Care Centers, Cross-Sectional Studies, Vitamin D and neurology, Medicine, Alkaline phosphatase, Humans, Female, medicine.symptom, Vitamin D, business
الوصف: Vitamin D plays a vital role in the maintenance of bone health. The fetuses and exclusively breastfed neonates depend on maternal vitamin D store to meet their need. Widespread vitamin D deficiency among pregnant women have been reported with adverse fetal outcome. Nigeria lacks guideline on Vitamin D supplementation in pregnancy and infancy due to the paucity of data. We thus determined serum vitamin D of delivering mothers and their offsprings and other indicators of bone mineral health.This study aimed to determine serum Vitamin D and other indicators of bone mineral health of delivering mothers and their offspring.A cross-sectional study of delivering mothers and their newborns recruited consecutively until the minimal sample size was reached. Relevant information was obtained on a questionnaire. Maternal and cord serum vitamin D, calcium, albumin, phosphate, and alkaline phosphatase were determined. Data management was done using SPSS version 16.0.Of the 84 newborn-mother pairs studied, 17 (20.2%) of the mothers were Vitamin D deficient and 23 (27.4%) insufficient. Seven (8.3%) of the mothers were hypocalcaemic and 3 (3.6%) hypophosphataemic, while 19 (22.6%) had elevated alkaline phosphatase. Only 15 (17.9%) of the neonates were vitamin D insufficient and none of them was vitamin D deficient, hypocalcaemic, hypophosphataemic nor had elevated alkaline phosphatase. There was strong positive correlation between cord and maternal blood vitamin D level (r = 0.740, P =0.001).Vitamin D deficiency and insufficiency is high among pregnant women in Maiduguri while insufficiency is common among the neonates. We recommend vitamin D supplementation to pregnant women and newborns in Maiduguri.
تدمد: 1119-3077
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6045222ec91545060e14ddba46ac7e00
https://pubmed.ncbi.nlm.nih.gov/33723108
رقم الأكسشن: edsair.doi.dedup.....6045222ec91545060e14ddba46ac7e00
قاعدة البيانات: OpenAIRE