Global patterns of phylogenetic diversity and transmission of bat coronavirus
| العنوان: | Global patterns of phylogenetic diversity and transmission of bat coronavirus |
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| المؤلفون: | Zhilin, Wang, Guangping, Huang, Mingpan, Huang, Qiang, Dai, Yibo, Hu, Jiang, Zhou, Fuwen, Wei |
| المصدر: | Science China Life Sciences. 66:861-874 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | General Agricultural and Biological Sciences, General Biochemistry, Genetics and Molecular Biology, General Environmental Science |
| الوصف: | Bats are reservoirs for multiple coronaviruses (CoVs). However, the phylogenetic diversity and transmission of global bat-borne CoVs remain poorly understood. Here, we performed a Bayesian phylogeographic analysis based on 3,594 bat CoV RdRp gene sequences to study the phylogenetic diversity and transmission of bat-borne CoVs and the underlying driving factors. We found that host-switching events occurred more frequently for α-CoVs than for β-CoVs, and the latter was highly constrained by bat phylogeny. Bat species in the families Molossidae, Rhinolophidae, Miniopteridae, and Vespertilionidae had larger contributions to the cross-species transmission of bat CoVs. Regions of eastern and southern Africa, southern South America, Western Europe, and Southeast Asia were more frequently involved in cross-region transmission events of bat CoVs than other regions. Phylogenetic and geographic distances were the most important factors limiting CoV transmission. Bat taxa and global geographic hotspots associated with bat CoV phylogenetic diversity were identified, and bat species richness, mean annual temperature, global agricultural cropland, and human population density were strongly correlated with the phylogenetic diversity of bat CoVs. These findings provide insight into bat CoV evolution and ecological transmission among bat taxa. The identified hotspots of bat CoV evolution and transmission will guide early warnings of bat-borne CoV zoonotic diseases. |
| تدمد: | 1869-1889 1674-7305 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f99cca57d7a5d9dd03c1da35bbad05 https://doi.org/10.1007/s11427-022-2221-5 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....64f99cca57d7a5d9dd03c1da35bbad05 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18691889 16747305 |
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