Computed tomography, magnetic resonance imaging and positron emission tomography with [18F] fluorodeoxyglucose in multiple system atrophy and pure autonomic failure
العنوان: | Computed tomography, magnetic resonance imaging and positron emission tomography with [18F] fluorodeoxyglucose in multiple system atrophy and pure autonomic failure |
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المؤلفون: | Mark Hallett, M. T. Curras, S. M. Baser, Richard M. Dubinsky, Michael J. Fulham, Rodney A. Brooks, R T Brown, G. Di Chiro, Ronald J. Polinsky |
المصدر: | Clinical Autonomic Research. 1:27-36 |
بيانات النشر: | Springer Science and Business Media LLC, 1991. |
سنة النشر: | 1991 |
مصطلحات موضوعية: | Male, Fluorine Radioisotopes, Cerebellum, medicine.medical_specialty, Deoxyglucose, Atrophy, Neuroimaging, Fluorodeoxyglucose F18, medicine, Humans, Pure autonomic failure, Retrospective Studies, Fluorodeoxyglucose, medicine.diagnostic_test, Endocrine and Autonomic Systems, business.industry, Putamen, Brain, Magnetic resonance imaging, Middle Aged, medicine.disease, Magnetic Resonance Imaging, medicine.anatomical_structure, Autonomic Nervous System Diseases, Positron emission tomography, Female, Cerebellar atrophy, Neurology (clinical), Radiology, Tomography, X-Ray Computed, Nuclear medicine, business, Brain Stem, Tomography, Emission-Computed, medicine.drug |
الوصف: | We studied 45 patients who had autonomic failure with computed tomography, magnetic resonance imaging and positron emission tomography with [18F]fluorodeoxyglucose to characterize the neuroimaging features of multiple system atrophy and pure autonomic failure and determine the utility of these techniques in distinguishing multiple system atrophy from pure autonomic failure. There were 30 patients with multiple system atrophy and 15 with pure autonomic failure. In the multiple system atrophy group, eight patients had mainly cerebellar signs, seven extrapyramidal and 15 had combinations of cerebellar and extrapyramidal signs. Cerebellar atrophy on computerized tomography and magnetic resonance imaging, signal hypointensity in the posterolateral putamen on magnetic resonance imaging and a generalized reduction in glucose utilization rate with positron emission tomography with [18F]fluorodeoxyglucose, were the main findings and were seen only in the patients with multiple system atrophy. Decreased glucose utilization (hypometabolism) was most prominent in the cerebellum, brainstem, striatum and frontal and motor cortices. These results indicate clear differences, using neuroimaging studies, between multiple system atrophy and pure autonomic failure. |
تدمد: | 1619-1560 0959-9851 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6caafb289419a94fa425feb7c07bcdf1 https://doi.org/10.1007/bf01826055 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....6caafb289419a94fa425feb7c07bcdf1 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 16191560 09599851 |
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