التفاصيل البيبلوغرافية
العنوان:
Generation and characterization of avian-derived anti-human CD19 single chain fragment antibodies
المؤلفون:
Yu Ching Lee , Wang Chuan Chen , Chang Yu Chang , Keng-Chang Tsai , Fu Ling Chang , Chen Wei Chiang , Yan Ni Lo , Tsai Yu Lin
المصدر:
Animal biotechnology . 30(4)
سنة النشر:
2018
مصطلحات موضوعية:
0301 basic medicine , Models, Molecular , Phage display , Molecular model , Antigens, CD19 , chemical and pharmacologic phenomena , Bioengineering , Computational biology , Biology , CD19 , 03 medical and health sciences , immune system diseases , hemic and lymphatic diseases , Cell Line, Tumor , medicine , Single-chain variable fragment , Animals , Humans , Cluster of differentiation , Fragment (computer graphics) , 0402 animal and dairy science , hemic and immune systems , 04 agricultural and veterinary sciences , Surface Plasmon Resonance , medicine.disease , 040201 dairy & animal science , Complementarity Determining Regions , Leukemia , 030104 developmental biology , biology.protein , Animal Science and Zoology , Antibody , Cell Surface Display Techniques , Chickens , Biotechnology , Single-Chain Antibodies
الوصف:
The human cluster of differentiation 19 (CD19) is highly expressed in most leukemia, rendering is a promising therapeutic target. In this study, we generated anti-CD19 single-chain variable fragments (scFv) from immunized chickens by phage display technology. After constructing a scFv antibody library with 2.5 × 10
تدمد:
1532-2378
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec5a83cbc924b6f3fbcc7b17cddb3e8 https://pubmed.ncbi.nlm.nih.gov/30261812
رقم الأكسشن:
edsair.doi.dedup.....6ec5a83cbc924b6f3fbcc7b17cddb3e8
قاعدة البيانات:
OpenAIRE
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