التفاصيل البيبلوغرافية
| العنوان: |
Supplementary Figures 1 - 6 from Combined Inhibition of MAP Kinase and KIT Signaling Synergistically Destabilizes ETV1 and Suppresses GIST Tumor Growth |
| المؤلفون: |
Ping Chi, Yu Chen, Cristina R. Antonescu, Peter Besmer, Ingo K. Mellinghoff, William D. Tap, Takahiro Taguchi, John Wongvipat, Ferdinando Rossi, Sinan Zhu, Dong Gao, Michael C. Kaufmann, Yuanyuan Xie, Shipra Shukla, Yuedan Chen, Devan Murphy, Zhen Cao, Inna Sirota, Leili Ran |
| بيانات النشر: |
American Association for Cancer Research (AACR), 2023. |
| سنة النشر: |
2023 |
| الوصف: |
Supplementary Figure 1: Etv1 is required for intramuscular and myenteric ICC development. Supplementary Figure 2: Etv1 ablation with tamoxifen decreases Etv1 and Kit expression in Kit^delta558/+;Etv1^flox/flox;Rosa26^CreERT2/CreERT2 mice. Supplementary Figure 3: Etv1 positively regulates Kit expression in murine stomach. Supplementary Figure 4: ETV1 regulates KIT expression in GIST48 cells. Supplementary Figure 5: MAP kinase pathway inhibition decreases ETV1 target gene expression. Supplementary Figure 6: Dual lineage inhibition inhibits tumor initiation in vivo. |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75960034644fb3105568d252a04acf5a
https://doi.org/10.1158/2159-8290.22530678.v1 |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.doi.dedup.....75960034644fb3105568d252a04acf5a |
| قاعدة البيانات: |
OpenAIRE |
