Multiple retroviral infection by HTLV type 1, 2, 3 and simian foamy virus in a family of Pygmies from Cameroon

التفاصيل البيبلوغرافية
العنوان: Multiple retroviral infection by HTLV type 1, 2, 3 and simian foamy virus in a family of Pygmies from Cameroon
المؤلفون: Sylviane Bassot, Alain Froment, Sébastien Chevalier, Edouard Betsem, Renaud Mahieux, Antoine Gessain, Patricia Tortevoye, Richard Njouom, Sara Calattini
المساهمون: Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Centre Pasteur du Cameroun, Réseau International des Instituts Pasteur (RIIP), Virologie humaine, École normale supérieure de Lyon (ENS de Lyon)-IFR128-Institut National de la Santé et de la Recherche Médicale (INSERM), Patrimoines Locaux et Gouvernance (PALOC), Muséum national d'Histoire naturelle (MNHN)-Institut de Recherche pour le Développement (IRD), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Lyon (ENS Lyon)-IFR128-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Virology
Virology, 2010, epub ahead of print. ⟨10.1016/j.virol.2010.10.025⟩
Virology, Elsevier, 2010, epub ahead of print. ⟨10.1016/j.virol.2010.10.025⟩
سنة النشر: 2010
مصطلحات موضوعية: Male, viruses, Simian foamy virus, Retrovirus, immune system diseases, hemic and lymphatic diseases, Cameroon, Child, Retroviral emergence, Phylogeny, 0303 health sciences, Simian foamy viruses, Pygmies, Transmission (medicine), transmission, virus diseases, Middle Aged, 3. Good health, Pedigree, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Female, Adult, Adolescent, Primate T-lymphotropic virus 2, Primate T-lymphotropic virus 1, Molecular Sequence Data, Primate T-lymphotropic virus 3, Biology, Virus, 03 medical and health sciences, Young Adult, Virology, Hunting, Humans, Family, 030304 developmental biology, Aged, 030306 microbiology, Retroviral infection, Central africa, biology.organism_classification, Chimpanzee foamy virus, HTLV-3, HTLV-2, HTLV-1, Immunology, Foamy Viruses, Retroviridae Infections
الوصف: International audience; To better understand the origins and modes of transmission of HTLV-3 and to search for other retroviral infections (HTLV-1, HTLV-2, foamy viruses), we studied the family of a HTLV-3-infected individual (Pyl43), from Cameroon. Thirty-five persons were included. All adult men were still actively hunting nonhuman primates (NHP). All women were also butchering and cutting-up animals. Five persons reported a bite by an NHP. While HTLV-3 infection was only found in Pyl43, HTLV-1 and HTLV-2 infections were found, respectively, in 5 and 9 persons with one being co-infected by both retroviruses. Phylogenetic analysis suggested intra-familial transmission of HTLV-1 subtypes B and D and HTLV-2. One man was infected by a chimpanzee foamy virus, acquired probably 45years ago, through a bite. Acquisition of retroviral infections still occurs in central Africa involving to various extent not only intra-familial transmission for HTLV-1/HTLV-2 but also direct interspecies transmission from NHP for foamy virus and possibly for HTLV-1 and HTLV-3.
تدمد: 1096-0341
0042-6822
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a6e32b86d9cdda396ce5a776b74275
https://pubmed.ncbi.nlm.nih.gov/21087785
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....76a6e32b86d9cdda396ce5a776b74275
قاعدة البيانات: OpenAIRE