New Ultra-minimally Invasive Surgical Treatment for Benign Prostatic Hyperplasia: A Systematic Review and Analysis of Comparative Outcomes
| العنوان: | New Ultra-minimally Invasive Surgical Treatment for Benign Prostatic Hyperplasia: A Systematic Review and Analysis of Comparative Outcomes |
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| المؤلفون: | Domenico Veneziano, Francesco Porpiglia, Federico Piramide, Juan Gómez Rivas, Zhamshid Okhunov, Enrico Checcucci, Gabriele Volpi, Angela Pecoraro, J. Meziere, Giovanni Cacciamani, Beatrice Carbonaro, D. Zamengo, Giorgio Ivan Russo, Sabrina De Cillis, S. Granato, Stefano De Luca, S. Puliatti, Cristian Fiori, M. Sica, P. Verri, Umberto Carbonara, Alberto Piana, S. Piscitello, Daniele Amparore, Alessandro Veccia, Riccardo Autorino, Mark Taratkin, Matteo Manfredi, José Marenco |
| المصدر: | European Urology Open Science, Vol 33, Iss, Pp 28-41 (2021) European Urology Open Science |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Urology, Context (language use), Quality of life, Lower urinary tract symptoms, Micturition, Internal medicine, Medicine, Ejaculation, RC254-282, Benign prostatic hyperplasia, Ultra-minimally invasive, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Review – Benign Prostatic Hyperplasia, Perioperative, medicine.disease, Prostatic artery embolization, Confidence interval, Diseases of the genitourinary system. Urology, International Prostate Symptom Score, RC870-923, business, Sexual function |
| الوصف: | Context Benign prostatic hyperplasia (BPH) associated with lower urinary tract symptoms (LUTS) is diagnosed in up to 80% of men during their lifetime. Several novel ultra-minimally invasive surgical treatments (uMISTs) for BPH/benign prostatic obstruction (BPO) have become available over the past 5 yr. Objective To evaluate the perioperative and functional outcomes of recently introduced uMISTs for BPH/BPO, including Urolift, Rezūm, temporary implantable nitinol device, prostatic artery embolization (PAE), and intraprostatic injection. Evidence acquisition A systematic literature search was conducted in December 2020 using Medline (via PubMed), Embase (via Ovid), Scopus, and Web of Science (registered on PROSPERO as CRD42021225014). The search strategy used PICO criteria and article selection was conducted in accordance with the PRISMA guidelines. The risk of bias and the quality of the articles included were assessed. A dedicated data extraction form was used to collect the data of interest. Pooled and cumulative analyses were performed to compare perioperative and functional outcomes between study groups. A random-effects model using the DerSimonian and Laird method was used to evaluate heterogeneity. Stata version 15.0 software was used for all statistical analyses. Evidence synthesis The initial electronic search identified 3978 papers, of which 48 ultimately met the inclusion criteria and were included in the analysis. Pooled analysis revealed a uMIST benefit in terms of International Prostate Symptom Score (IPSS; −9.81 points, 95% confidence interval [CI] −11.37 to −8.25 at 1 mo; −13.13 points, 95% CI −14.98 to −11.64 at 12 mo), maximum flow rate (from +3.66 ml/s, 95% CI 2.8–4.5 to +4.14 ml/s, 95% CI 0.72–7.56 at 12 mo), and postvoid residual volume (−10.10 ml, 95% CI −27.90 to 7.71 at 12 mo). No negative impact was observed on scores for the International Index of Erectile Function-5, Male Sexual Health Questionnaire-Ejaculatory Dysfunction bother and function scales (overall postintervention change in pooled median score of 1.88, 95% CI 1.34–2.42 at the start of follow-up; and 1.04, 95% CI 0.28–1.8 after 1 yr), or the IPSS-Quality of Life questionnaire. Conclusions Novel uMISTs can yield fast and effective relief of LUTS without affecting patient quality of life. Only Rezūm, UroLift, and PAE had a minimal impact on patients’ sexual function with respect to baseline, especially regarding preservation of ejaculation. Patient summary We reviewed outcomes for recently introduced ultra-minimally invasive surgical treatments for patients with lower urinary tract symptoms caused by benign prostate enlargement or obstruction. The evidence suggests that these novel techniques are beneficial in terms of controlling symptoms while preserving sexual function. Take Home Message Novel ultra-minimally invasive treatments can yield fast and effective relief of lower urinary tract symptoms without affecting a patient’s quality of life. |
| اللغة: | English |
| تدمد: | 2666-1683 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878ae618a19af0f6e965e202f2281e2d http://www.sciencedirect.com/science/article/pii/S266616832100673X |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....878ae618a19af0f6e965e202f2281e2d |
| قاعدة البيانات: | OpenAIRE |
Full Text via ClinicalKey | تدمد: | 26661683 |
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