Mesenteric occlusive disease of the inferior mesenteric artery is associated with anastomotic leak after left-sided colon and rectal cancer surgery: a retrospective cohort study
| العنوان: | Mesenteric occlusive disease of the inferior mesenteric artery is associated with anastomotic leak after left-sided colon and rectal cancer surgery: a retrospective cohort study |
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| المؤلفون: | Melissa N. N. Arron, Richard P. G. ten Broek, Carleen M. E. M. Adriaansens, Stijn Bluiminck, Bob J. van Wely, Floris T. J. Ferenschild, Henk F. M. Smits, Harry van Goor, Johannes H. W. de Wilt, André S. van Petersen |
| المصدر: | International Journal of Colorectal Disease, 37, 3, pp. 631-638 International Journal of Colorectal Disease, 37, 631-638 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cohort Studies, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], Colon, Rectal Neoplasms, Anastomosis, Surgical, Gastroenterology, Humans, Anastomotic Leak, Mesenteric Artery, Inferior, Retrospective Studies |
| الوصف: | Purpose Anastomotic leak (AL) is a serious complication following colorectal surgery. Atherosclerosis causes inadequate anastomotic perfusion and is suggested to be a risk factor for AL. The aim of this study was to investigate the association of mesenteric occlusive disease on preoperative computed tomography (CT) scan with AL after left-sided colon or rectal cancer surgery. Methods This was a retrospective, multicenter cohort study including 1273 patients that underwent left-sided or rectal cancer resection between 2009 and 2018 from three hospitals in the Netherlands. AL patients were 1:1 matched with non-leak patients and preoperative contrast-enhanced CT-scans were retrospectively analyzed for mesenteric atherosclerotic lesions. The main outcome measure was the presence of mesenteric occlusive disease on the preoperative CT-scan. Results Anastomotic leak developed in 6% of 1273 patients (N = 76). Low anterior resection and stage I–III disease were statistically significant associated with AL (p = 0.01, p = 0.04). No other statistically significant differences in patient characteristics between AL and non-leak patients were found. A clinically significant stenosis (≥ 70–100%) of the inferior mesenteric artery was statistically significant more frequent present in AL patients, compared to non-leak patients (p Conclusion Mesenteric occlusive disease of the IMA on preoperative CT-scan is associated with AL after left-sided colon or rectal resection for cancer. Preoperative identification of high-risk patients with a preoperative CT-scan of the mesenteric vasculature might be useful to reduce the risk of AL. |
| وصف الملف: | application/pdf |
| تدمد: | 1432-1262 0179-1958 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8862a65219fec80b239e3b9aefd6cb78 https://doi.org/10.1007/s00384-021-04089-0 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8862a65219fec80b239e3b9aefd6cb78 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321262 01791958 |
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