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Current Perspectives on Aerobic Exercise in People with Parkinson’s Disease

التفاصيل البيبلوغرافية
العنوان: Current Perspectives on Aerobic Exercise in People with Parkinson’s Disease
المؤلفون: Nienke M. de Vries, Sabine Schootemeijer, Bastiaan R. Bloem, Nicolien M. van der Kolk
المصدر: Neurotherapeutics
بيانات النشر: Springer International Publishing, 2020.
سنة النشر: 2020
مصطلحات موضوعية: medicine.medical_specialty, Neurology, Parkinson's disease, Physical fitness, Neurological disorder, Disease, Review, 03 medical and health sciences, mobility limitation, 0302 clinical medicine, Quality of life (healthcare), Physical medicine and rehabilitation, endurance training, Endurance training, Medicine, Aerobic exercise, Humans, Pharmacology (medical), 030212 general & internal medicine, Exercise, Pharmacology, business.industry, Parkinson Disease, medicine.disease, Exercise Therapy, locomotion, health-related quality of life, Physical Fitness, Quality of Life, Parkinson’s disease, Neurology (clinical), business, 030217 neurology & neurosurgery
الوصف: Parkinson’s disease (PD) is a progressive neurological disorder characterized by motor and non-motor symptoms for which only symptomatic treatments exist. Exercise is a widely studied complementary treatment option. Aerobic exercise, defined as continuous movement of the body’s large muscles in a rhythmic manner for a sustained period that increases caloric requirements and aims at maintaining or improving physical fitness, appears promising. We performed both a scoping review and a systematic review on the generic and disease-specific health benefits of aerobic exercise for people with PD. We support this by a meta-analysis on the effects on physical fitness (VO2max), motor symptoms (Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) motor section), and health-related quality of life (39-item Parkinson’s disease Questionnaire (PDQ-39)). Aerobic exercise has generic health benefits for people with PD, including a reduced incidence of cardiovascular disease, a lower mortality, and an improved bone health. Additionally, there is level 1 evidence that aerobic exercise improves physical fitness (VO2max) and attenuates motor symptoms (MDS-UPDRS motor section) in the off-medication state, although the long-term effects (beyond 6 months) remain unclear. Dosing the exercise matters: improvements appear to be greater after training at higher intensities compared with moderate intensities. We found insufficient evidence for a beneficial effect of aerobic exercise on health-related quality of life (PDQ-39) and conflicting results regarding non-motor symptoms. Compliance to exercise regimes is challenging for PD patients but may be improved by adding exergaming elements to the training program. Aerobic exercise seems a safe intervention for people with PD, although care must be taken to avoid falls in at-risk individuals. Further studies are needed to establish the long term of aerobic exercise, including a focus on non-motor symptoms and health-related quality of life. Electronic supplementary material The online version of this article (10.1007/s13311-020-00904-8) contains supplementary material, which is available to authorized users.
اللغة: English
تدمد: 1878-7479
1933-7213
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c3a76524eeba4411c0e1d5c7d093e
http://europepmc.org/articles/PMC7851311
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....8e5c3a76524eeba4411c0e1d5c7d093e
قاعدة البيانات: OpenAIRE
الوصف
تدمد:18787479
19337213