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Histoplasma capsulatum and Pneumocystis spp. co-infection in wild bats from Argentina, French Guyana, and Mexico

التفاصيل البيبلوغرافية
العنوان: Histoplasma capsulatum and Pneumocystis spp. co-infection in wild bats from Argentina, French Guyana, and Mexico
المؤلفون: Christine Demanche, José Antonio Ramírez-Bárcenas, Maria Lucia Taylor, Cécile M Aliouat-Denis, El Moukhtar Aliouat, Antonio E. González-González, Muriel Pottier, Laura E. Carreto-Binaghi, Magalie Chabé, Eduardo Dei-Cas, Sandra Derouiche, Haroon Akbar
المساهمون: Department of Microbiology and Parasitology, Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Service de Parasitologie-Mycologie [CHRU LIlle], Institut de Microbiologie [CHRU Lille], Pôle de Biologie Pathologie Génétique [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Pôle de Biologie Pathologie Génétique [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), The present research was supported by the following grants: SEP-CONACYT-ANUIES-ECOS-M05-A03 (Mexico-France) and DGAPA- PAPIIT -Ref. No. IN-203407-3, UNAM, Mexico. A. E. González-González thanks the Biological Science Graduate Program of UNAM and the scholarship of CONACYT (Ref. No. 23492), BMC, Ed., National Autonomous University of Mexico, Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Service de Parasitologie-Mycologie, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)
المصدر: BMC Microbiology
BMC Microbiology, 2014, 14 (1), pp.23. ⟨10.1186/1471-2180-14-23⟩
BMC Microbiology, BioMed Central, 2014, 14 (1), pp.23. ⟨10.1186/1471-2180-14-23⟩
بيانات النشر: BioMed Central, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Microbiology (medical), Population, Histoplasma, Molecular Sequence Data, Argentina, Microbiology, Polymerase Chain Reaction, Histoplasmosis, Chiroptera, parasitic diseases, Bats, medicine, Animals, education, Pathogen, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, Mexico, education.field_of_study, biology, Pneumocystis, Coinfection, Sequence Analysis, DNA, biology.organism_classification, medicine.disease, bacterial infections and mycoses, Co-infection, Pneumocystis Infections, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, PCR, Parasitology, RNA, Ribosomal, Mammal, Guyana, Research Article
الوصف: Background Histoplasma capsulatum and Pneumocystis organisms cause host infections primarily affecting the lung tissue. H. capsulatum is endemic in the United States of America and Latin American countries. In special environments, H. capsulatum is commonly associated with bat and bird droppings. Pneumocystis-host specificity has been primarily studied in laboratory animals, and its ability to be harboured by wild animals remains as an important issue for understanding the spread of this pathogen in nature. Bats infected with H. capsulatum or Pneumocystis spp. have been found, with this mammal serving as a probable reservoir and disperser; however, the co-infection of bats with both of these microorganisms has never been explored. To evaluate the impact of H. capsulatum and Pneumocystis spp. infections in this flying mammal, 21 bat lungs from Argentina (AR), 13 from French Guyana (FG), and 88 from Mexico (MX) were screened using nested-PCR of the fragments, employing the Hcp100 locus for H. capsulatum and the mtLSUrRNA and mtSSUrRNA loci for Pneumocystis organisms. Results Of the 122 bats studied, 98 revealed H. capsulatum infections in which 55 of these bats exhibited this infection alone. In addition, 51 bats revealed Pneumocystis spp. infection of which eight bats exhibited a Pneumocystis infection alone. A total of 43 bats (eight from AR, one from FG, and 34 from MX) were found co-infected with both fungi, representing a co-infection rate of 35.2% (95% CI = 26.8-43.6%). Conclusion The data highlights the H. capsulatum and Pneumocystis spp.co-infection in bat population’s suggesting interplay with this wild host.
وصف الملف: application/pdf
اللغة: English
تدمد: 1471-2180
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d195ada39725e02af869c5718aea15
http://europepmc.org/articles/PMC3916801
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....91d195ada39725e02af869c5718aea15
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14712180