Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts
| العنوان: | Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts |
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| المؤلفون: | Tetiana Ilina, Nadiya Tryshchuk, Sergiy M. Kovalenko, Igor Kireyev, Yevhen Romanenko, Oleh Koshovyi, N. D. Bunyatyan, Ain Raal |
| المصدر: | Plants Volume 10 Issue 2 Plants, Vol 10, Iss 230, p 230 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Hyperoside, Plant Science, 01 natural sciences, chemistry.chemical_compound, dry extract, Caffeic acid, Ecology, Evolution, Behavior and Systematics, tincture, modification, Ecology, Traditional medicine, biology, 010405 organic chemistry, Botany, psychotropic activity, Tincture, Catechin, Leonurus cardiaca, biology.organism_classification, Motherwort, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Phytochemical, QK1-989, Leonurus cardiaca L, biological active substances, amino acid, Ellagic acid |
| الوصف: | The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and rosmarinic acids). The dominant hydroxycinnamic acids were chlorogenic and caffeic acids. Among flavonoids, catechin, hyperoside, and rutin were identified. It should be noted that the extracts had a significant content of ellagic acid. On the basis of the results of the phytochemical analysis of the extracts, it can be concluded that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which obviously have an impact on the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the motherwort extracts studied in complex with amino acids. The extracts with glycine, valine, and arginine were more effective in reducing anxiety in animals. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2223-7747 |
| DOI: | 10.3390/plants10020230 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940adba77f152f0b0401e0618fdc74d1 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....940adba77f152f0b0401e0618fdc74d1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22237747 |
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| DOI: | 10.3390/plants10020230 |