HIV prevalence in suspected Ebola cases during the 2014–2016 Ebola epidemic in Sierra Leone
| العنوان: | HIV prevalence in suspected Ebola cases during the 2014–2016 Ebola epidemic in Sierra Leone |
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| المؤلفون: | Yang Liu, Shao-Jian Cai, Xiao-Ping Dong, Yuelong Shu, Patricia Ongpin, Michael Gboun, Hai-Yang Hu, Guizhen Wu, Zhe Zhang, Qiu-Dong Su, Xian-da Yang, Xiu-Xu Yang, Dapeng Sun, Abdul Kamara, Wenbo Xu, William J. Liu, Yulan Sun, George F. Gao, Matt Lebby, Brima Kargbo, Idrissa Kamara |
| المصدر: | Infectious Diseases of Poverty Infectious Diseases of Poverty, Vol 8, Iss 1, Pp 1-4 (2019) |
| بيانات النشر: | BioMed Central, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Hepatitis C virus, 030231 tropical medicine, Case Report, HIV Infections, Disease, medicine.disease_cause, lcsh:Infectious and parasitic diseases, Sierra leone, Sierra Leone, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Acquired immunodeficiency syndrome (AIDS), Environmental health, medicine, Prevalence, Humans, lcsh:RC109-216, 030212 general & internal medicine, Child, Epidemics, Ebola virus, business.industry, lcsh:Public aspects of medicine, Public health, Public Health, Environmental and Occupational Health, Infant, Newborn, Outbreak, virus diseases, HIV, Infant, lcsh:RA1-1270, General Medicine, Hemorrhagic Fever, Ebola, Middle Aged, medicine.disease, Infectious Diseases, Cross-Sectional Studies, Child, Preschool, Tropical medicine, HCV, Ebola, Female, business |
| الوصف: | Background The 2014–2016 Ebola virus epidemic in West Africa was the largest outbreak of Ebola virus disease (EVD) in history. Clarifying the influence of other prevalent diseases such as human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) will help improve treatment and supportive care of patients with EVD. Case presentation We examined HIV and hepatitis C virus (HCV) antibody prevalence among suspected EVD cases from the Sierra Leone-China Friendship Biological Safety Laboratory during the epidemic in Sierra Leone. HIV and HCV antibodies were tested in 678 EVD-negative samples by enzyme-linked immunosorbent assay. A high HIV prevalence (17.6%) and low HCV prevalence (0.22%) were observed among the suspected cases. Notably, we found decreased HIV positive rates among the suspected cases over the course of the epidemic. This suggests a potentially beneficial effect of an improved public health system after assistance from the World Health Organization and other international aid organizations. Conclusions This EVD epidemic had a considerable impact on the public health system and influenced the prevalence of HIV found among suspected cases in Sierra Leone, but also provided an opportunity to establish a better surveillance network for infectious diseases. Electronic supplementary material The online version of this article (10.1186/s40249-019-0525-9) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 2049-9957 2095-5162 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972cfb87d84d2939e59b59bd2c362bcb http://europepmc.org/articles/PMC6398227 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....972cfb87d84d2939e59b59bd2c362bcb |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 20499957 20955162 |
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