Comparative proteomic analysis of melanosis coli with colon cancer
| العنوان: | Comparative proteomic analysis of melanosis coli with colon cancer |
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| المؤلفون: | La-Mei Zhang, Li-Ping Xu, Huan-Huan Su, Xiao-Min Liu, Ping Wang, Xin Zhou, Lin Zhu, Jin-Jin Xu, Ying-Jian Zhang |
| المصدر: | Oncology Reports. 36:3700-3706 |
| بيانات النشر: | Spandidos Publications, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Proteomics, 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, Proteome, Colon, Cell, Biology, medicine.disease_cause, Melanosis, 03 medical and health sciences, 0302 clinical medicine, Melanosis coli, Biomarkers, Tumor, medicine, Humans, Electrophoresis, Gel, Two-Dimensional, Gene, Gel electrophoresis, Oncogene, General Medicine, medicine.disease, Molecular medicine, Molecular biology, 030104 developmental biology, medicine.anatomical_structure, Oncology, Case-Control Studies, 030220 oncology & carcinogenesis, Colonic Neoplasms, Carcinogenesis |
| الوصف: | The present study aimed to investigate the proteomic difference between melanosis coli (MC) alone and melanosis coli with colon cancer (MCCC). Protein expression in patients with different diseases was analyzed using two-dimensional gel electrophoresis and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/TOF-MS). A total of 14 protein differences with a confidence level of >95% were found. There were six differences between MC and normal tissues, in which two proteins exhibited upregulated expression levels and four proteins exhibited downregulated expression levels in MC. Furthermore, one protein was expressed only in MC (P |
| تدمد: | 1791-2431 1021-335X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d5487222cdca38d411e780b91a0d55 https://doi.org/10.3892/or.2016.5178 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a0d5487222cdca38d411e780b91a0d55 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17912431 1021335X |
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