Effects of Misoprostol on Induction of Labour in Patients with Hypertensive Disorders of Pregnancy: A Meta-Analysis
| العنوان: | Effects of Misoprostol on Induction of Labour in Patients with Hypertensive Disorders of Pregnancy: A Meta-Analysis |
|---|---|
| المؤلفون: | Leilei Wang, Sishi Liu, Guiyu Song, Man Gao, Tong Liu |
| المصدر: | Journal of Healthcare Engineering. 2022:1-6 |
| بيانات النشر: | Hindawi Limited, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Article Subject, Postpartum Hemorrhage, Biomedical Engineering, Health Informatics, Hypertension, Pregnancy-Induced, Oxytocin, Pregnancy, Oxytocics, Humans, Female, Surgery, Labor, Induced, Misoprostol, Biotechnology |
| الوصف: | Objective. Hypertensive disorders of pregnancy (HDP) can cause serious prenatal and postnatal complications and is a threat to maternal and fetal health. To offer guidance for clinical decisions, we systematically reviewed the effects of misoprostol on induction of labour in HDP patients. Methods. PubMed, Web of Science, Embase, CNKI, and Wanfang databases were searched for relevant literature from 2010 to 2020. Subsequently, a meta-analysis was performed to compare the effective rate of induction of labour and reducing postpartum hemorrhage (PPH) between the intervention group (n = 544, misoprostol) and the control group (n = 543, oxytocin). Results. A total of 10 studies with 1087 patients were included. The 10 studies compared the effective rate of induction of labour between the two groups and confirmed that the effective rate in the intervention group was significantly higher than that in the control group (OR = 4.37; 95% CI: 2.73, 7.00). Seven studies compared PPH between the groups and showed that it was significantly reduced in the intervention group compared to the control group (SMD = −1.32; 95% CI: −2.05, −0.59; P < 0.0001 ). Conclusion. Misoprostol has a high effective rate of induction of labour in HDP patients and is an effective uterotonic agent in reducing PPH. This meta-analysis provides clinicians with meaningful information to help them make evidence-based decisions. |
| وصف الملف: | text/xhtml |
| تدمد: | 2040-2309 2040-2295 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36d66f3d55ad2def7a6b1f421c077c3 https://doi.org/10.1155/2022/8448690 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....a36d66f3d55ad2def7a6b1f421c077c3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20402309 20402295 |
|---|