OPTIMAL CONDITIONS FOR THE OPSONOPHAGOCYTOSIS TEST WITH STREPTOCOCCUS PNEUMONIAE SEROTYPES 3, 6A, 7F AND 19F AND HUMAN GRANULOCYTES
| العنوان: | OPTIMAL CONDITIONS FOR THE OPSONOPHAGOCYTOSIS TEST WITH STREPTOCOCCUS PNEUMONIAE SEROTYPES 3, 6A, 7F AND 19F AND HUMAN GRANULOCYTES |
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| المؤلفون: | Markku Koskela, Sylvi Silvennoinen-Kassinen |
| المصدر: | Acta Pathologica Microbiologica Scandinavica Series C: Immunology. :105-111 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Serotype, Time Factors, Phagocytosis, Immunology, Dose-Response Relationship, Immunologic, Granulocyte, medicine.disease_cause, Antibodies, Microbiology, Streptococcus pneumoniae, medicine, Humans, Serotyping, General Immunology and Microbiology, biology, Complement System Proteins, General Medicine, Opsonin Proteins, Streptococcaceae, biology.organism_classification, Antibody opsonization, medicine.anatomical_structure, Evaluation Studies as Topic, biology.protein, Antibody, Bacteria, Granulocytes |
| الوصف: | There are great variations in test systems used to measure pneumococcal opsonophagocytosis; therefore, in the present study, a detailed analysis of the human granulocyte opsonophagocytosis test with pneumococci was made. Variables affecting the test were evaluated. These were the amount of bacteria, the amount of antipneumococcal antibody and complement in the test. Correlation between phagocytosis percentage (percentage of cells taking part in the phagocytosis) and phagocytosis index (mean amount of bacteria phagocytosed per cell) was shown. The conclusion is that, after precise test-adjustment, weak phagocytosis is better detected by phagocytosis percentage and high phagocytosis activity is best shown by phagocytosis index. |
| تدمد: | 0108-0202 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5035a8031a2413532aaf77e917d01ee https://doi.org/10.1111/j.1699-0463.1986.tb02098.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....a5035a8031a2413532aaf77e917d01ee |
| قاعدة البيانات: | OpenAIRE |
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