التفاصيل البيبلوغرافية
العنوان:
Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human
المؤلفون:
Hiroyuki Sasabe , Yosuke Kaneko , Masayuki Furukawa , Masayuki Matsunaga , Eiji Kashiyama , Yukihiro Hirao , Mitsuhiko Kawabata , Noriyuki Koyama , Toshihisa Koga , Hitomi Akazawa , Kenji Takeuchi
المصدر:
Xenobiotica; the fate of foreign compounds in biological systems . 51(5)
سنة النشر:
2021
مصطلحات موضوعية:
Serotonin , Health, Toxicology and Mutagenesis , Metabolite , Dopamine , Thiophenes , Pharmacology , Quinolones , Toxicology , 030226 pharmacology & pharmacy , Biochemistry , 03 medical and health sciences , chemistry.chemical_compound , 0302 clinical medicine , Pharmacokinetics , medicine , Animals , Humans , Brexpiprazole , Total body , General Medicine , Metabolism , Haplorhini , In vitro , Rats , chemistry , 030220 oncology & carcinogenesis , medicine.drug
الوصف:
The pharmacokinetics of brexpiprazole were investigated in the in vitro and in vivo.The total body clearance of brexpiprazole in rat and monkey was 2.32 and 0.326 L/h/kg, respectively, after intrav...
تدمد:
1366-5928
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7762bcff7a84c2ea001970b465d606 https://pubmed.ncbi.nlm.nih.gov/33685346
رقم الأكسشن:
edsair.doi.dedup.....ab7762bcff7a84c2ea001970b465d606
قاعدة البيانات:
OpenAIRE
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