التفاصيل البيبلوغرافية
العنوان:
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice
المؤلفون:
Qiuli Tong , Hu Liu , Qianqian Qi , Chaohui Dai , Teddy Yang , Feng Qian
المصدر:
FEBS Open Bio . 12:1542-1557
بيانات النشر:
Wiley, 2022.
سنة النشر:
2022
مصطلحات موضوعية:
Mice , Cell Line, Tumor , Glucocorticoid-Induced TNFR-Related Protein , Animals , Humans , Immunotherapy , Glucocorticoids , Antibodies , Receptors, Tumor Necrosis Factor , General Biochemistry, Genetics and Molecular Biology
الوصف:
Glucocorticoid-induced TNF receptor-related (GITR) can act as a co-stimulatory receptor, representing a potential target for safely enhancing immunotherapy efficacy. GITR is triggered by a GITR ligand or an agonist antibody and activates CD8
تدمد:
2211-5463
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac24d24c246b1d7d5993f4535dae8523 https://doi.org/10.1002/2211-5463.13451
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....ac24d24c246b1d7d5993f4535dae8523
قاعدة البيانات:
OpenAIRE
