Genotoxic effects of profenofos on the marine fish, Therapon jarbua

التفاصيل البيبلوغرافية
العنوان: Genotoxic effects of profenofos on the marine fish, Therapon jarbua
المؤلفون: M. Yokesh Babu, V. Janaki Devi, N. Vijayalakshimi, N. Nagarani, A.K. Kumaraguru
المصدر: Toxicology mechanisms and methods. 22(2)
سنة النشر: 2011
مصطلحات موضوعية: Veterinary medicine, Insecticides, Dose-Response Relationship, Drug, DNA damage, Health, Toxicology and Mutagenesis, Organothiophosphates, Profenofos, Fishes, Marine fish, Biology, Toxicology, Median lethal dose, Comet assay, Lethal Dose 50, chemistry.chemical_compound, chemistry, Organophosphorus insecticide, Animals, Therapon jarbua, Comet Assay, DNA Damage
الوصف: Profenofos (EC(50)) is a persistent and toxic organophosphorus insecticide. Animals get exposed to profenofos via food and water. The present study was designed to explore the genotoxic effect of profenofos in the marine fish. The ubiquitously occurring marine fish, Therapon jarbua, was exposed to profenofos and its effect on DNA was measured using comet (single-cell gel electrophoresis) assay. DNA damage were scored using mean percentage of tail length and compared with the comet classes' viz., 0, 1, 2, 3, and 4. In the first three doses, the (21.5, 43.0 and 86.0 µg L(-1)) comets were observed, of which the mean tail length differed significantly (p
تدمد: 1537-6524
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f31f12a6f833f10e749b6f60fe3b42
https://pubmed.ncbi.nlm.nih.gov/21859359
رقم الأكسشن: edsair.doi.dedup.....b3f31f12a6f833f10e749b6f60fe3b42
قاعدة البيانات: OpenAIRE