Characterization and mutagenesis of a novel Mycobacterium smegmatis-derived glutamate decarboxylase active at neutral pH
| العنوان: | Characterization and mutagenesis of a novel Mycobacterium smegmatis-derived glutamate decarboxylase active at neutral pH |
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| المؤلفون: | Yudi Li, Guiying Chen, Fanglan Ge, Ting Dang, Yao Ren, Bei Zeng, Wei Li |
| المصدر: | World Journal of Microbiology and Biotechnology. 38 |
| بيانات النشر: | Springer Science and Business Media LLC, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Molecular Docking Simulation, Glutamate Decarboxylase, Mutagenesis, Physiology, Mycobacterium smegmatis, General Medicine, Hydrogen-Ion Concentration, Applied Microbiology and Biotechnology, Biotechnology |
| الوصف: | γ-aminobutyric acid (GABA) has various physiological functions and is widely used in medicine, food, and other fields. Glutamate decarboxylase (GAD) is a key enzyme that catalyzes the decarboxylation of L-glutamate to synthesize GABA. However, the industrial application of microorganism-derived GAD is limited by its rapid loss of enzymatic activity with pH approaching neutrality. In this study, a novel glutamate decarboxylase, GAD |
| تدمد: | 1573-0972 0959-3993 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f6d40aa0c94c1387eb6d12776b5d9 https://doi.org/10.1007/s11274-022-03252-1 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....b41f6d40aa0c94c1387eb6d12776b5d9 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15730972 09593993 |
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