Clinical Outcomes of Acute Respiratory Failure Associated With Noninvasive and Invasive Ventilation in a Pediatric ICU
العنوان: | Clinical Outcomes of Acute Respiratory Failure Associated With Noninvasive and Invasive Ventilation in a Pediatric ICU |
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المؤلفون: | James M Kyle, Julie M Sturza, Ronald E Dechert, Joseph R Custer, Mary K Dahmer, Thomas G Saba, Heidi R Flori |
المصدر: | Respiratory care. 67(8) |
سنة النشر: | 2022 |
مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Intensive Care Units, Respiratory Distress Syndrome, Noninvasive Ventilation, Humans, General Medicine, Critical Care and Intensive Care Medicine, Child, Intensive Care Units, Pediatric, Respiratory Insufficiency, Respiration, Artificial |
الوصف: | It remains unknown if pediatric patients failing initial noninvasive ventilation (NIV) experience worse clinical outcomes than those successfully treated with NIV or those primarily intubated.This was a single-center, retrospective review of patients admitted with acute respiratory failure to the University of Michigan pediatric intensive care or cardiothoracic ICUs and receiving NIV or invasive mechanical ventilation as first-line therapy.One hundred seventy subjects met inclusion criteria and were enrolled: 65 NIV success, 55 NIV failure, and 50 invasive mechanical ventilation alone. Of those failing NIV, median time to intubation was 1.8 (interquartile range [IQR]1-7) h. On multivariable regression, ICU-free days were significantly different between groups (NIV success: 22.9 ± 6.9 d; NIV failure: 13.0We demonstrated that critically ill pediatric subjects unsuccessfully trialed on NIV did not experience increased ICU length of stay or fewer ventilator-free days when compared to those on invasive mechanical ventilation alone, including in the pediatric ARDS subgroup. Our findings are predicated on a median time to intubation of2 h in the NIV failure group and the provision of adequate monitoring while on NIV. |
تدمد: | 1943-3654 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d642d2aea59c32e1a509d8eb49a41c https://pubmed.ncbi.nlm.nih.gov/35701174 |
رقم الأكسشن: | edsair.doi.dedup.....b7d642d2aea59c32e1a509d8eb49a41c |
قاعدة البيانات: | OpenAIRE |
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