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High educational performance is a distinctive feature of bipolar disorder : A study on cognition in bipolar disorder, schizophrenia patients, relatives and controls

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العنوان: High educational performance is a distinctive feature of bipolar disorder : A study on cognition in bipolar disorder, schizophrenia patients, relatives and controls
المؤلفون: Vreeker, A., Boks, M.P.M., Abramovic, L., Verkooijen, S., Bergen, A.H. van, Hillegers, M.H.J., Spijker, A.T., Hoencamp, E., Regeer, E.J., Riemersma-Van der Lek, R.F., Stevens, A.W.M.M., Schulte, P.F.J., Vonk, R., Hoekstra, R., Beveren, N.J.M. van, Kupka, R.W., Brouwer, R.M., Bearden, C.E., MacCabe, J.H., Ophoff, R.A., Grp Investigators
المساهمون: EMGO - Mental health, Psychiatry, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, Adult Psychiatry, Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health, MUMC+: MA Psychiatrie (3), MUMC+: Hersen en Zenuw Centrum (3), Neurosciences
المصدر: Psychological Medicine, 46(4), 807-818. Cambridge University Press
Psychological Medicine, 46(4), 807. Cambridge University Press
Psychological medicine, 46(4), 807-818. Cambridge University Press
Psychological Medicine, 46(4), 807-818
Vreeker, A, Boks, M P M, Abramovic, L, Verkooijen, S, Van Bergen, A H, Hillegers, M H J, Spijker, A T, Hoencamp, E, Regeer, E J, Riemersma-Van Der Lek, R F, Stevens, A W M M, Schulte, P F J, Vonk, R, Hoekstra, R, Van Beveren, N J M, Kupka, R W, Brouwer, R M, Bearden, C E, MacCabe, J H & Ophoff, R A 2016, ' High educational performance is a distinctive feature of bipolar disorder : A study on cognition in bipolar disorder, schizophrenia patients, relatives and controls ', Psychological Medicine, vol. 46, no. 4, pp. 807-818 . https://doi.org/10.1017/S0033291715002299
Psychological medicine, vol 46, iss 4
Vreeker, A, Boks, M P M, Abramovic, L, Verkooijen, S, van Bergen, A H, Hillegers, M H J, Spijker, A T, Hoencamp, E, Regeer, E J, Riemersma-Van der Lek, R F, Stevens, A W M M, Schulte, P F J, Vonk, R, Hoekstra, R, van Beveren, N J M, Kupka, R W, Brouwer, R M, Bearden, C E, MacCabe, J H & Ophoff, R A 2016, ' High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, schizophrenia patients, relatives and controls ', Psychological Medicine, vol. 46, no. 4, pp. 807-818 . https://doi.org/10.1017/S0033291715002299
سنة النشر: 2016
مصطلحات موضوعية: Male, cognition, Cross-sectional study, POPULATION-BASED COHORT, NEUROCOGNITIVE ENDOPHENOTYPES, 0302 clinical medicine, 1ST-DEGREE RELATIVES, Odds Ratio, Psychology, HUMAN INTELLIGENCE, PREMORBID IQ, Young adult, Non-U.S. Gov't, Applied Psychology, familial vulnerability, Psychiatry, Intelligence Tests, education.field_of_study, Intelligence quotient, Research Support, Non-U.S. Gov't, Middle Aged, intelligence, Serious Mental Illness, educational performance, CANNABIS USE, Psychiatry and Mental health, Mental Health, Schizophrenia, Public Health and Health Services, Educational Status, Female, Schizophrenic Psychology, EUTHYMIC PATIENTS, Clinical psychology, Adult, medicine.medical_specialty, Bipolar disorder, AGE 16, Population, Research Support, Article, N.I.H, Young Adult, 03 medical and health sciences, Research Support, N.I.H., Extramural, Clinical Research, medicine, Journal Article, Humans, Family, education, Aged, business.industry, Neurosciences, Case-control study, Extramural, Odds ratio, Achievement, medicine.disease, Brain Disorders, 030227 psychiatry, Quality Education, schizophrenia, Cross-Sectional Studies, IQ, Case-Control Studies, SCHOOL PERFORMANCE, GROUP Investigators, business, 030217 neurology & neurosurgery, NATIONAL COHORT
الوصف: BackgroundSchizophrenia is associated with lower intelligence and poor educational performance relative to the general population. This is, to a lesser degree, also found in first-degree relatives of schizophrenia patients. It is unclear whether bipolar disorder I (BD-I) patients and their relatives have similar lower intellectual and educational performance as that observed in schizophrenia.MethodThis cross-sectional study investigated intelligence and educational performance in two outpatient samples [494 BD-I patients, 952 schizophrenia spectrum (SCZ) patients], 2231 relatives of BD-I and SCZ patients, 1104 healthy controls and 100 control siblings. Mixed-effects and regression models were used to compare groups on intelligence and educational performance.ResultsBD-I patients were more likely to have completed the highest level of education (odds ratio 1.88, 95% confidence interval 1.66–2.70) despite having a lower IQ compared to controls (β= −9.09,s.e.= 1.27,p< 0.001). In contrast, SCZ patients showed both a lower IQ (β= −15.31,s.e.= 0.86,p< 0.001) and lower educational levels compared to controls. Siblings of both patient groups had significantly lower IQ than control siblings, but did not differ on educational performance. IQ scores did not differ between BD-I parents and SCZ parents, but BD-I parents had completed higher educational levels.ConclusionsAlthough BD-I patients had a lower IQ than controls, they were more likely to have completed the highest level of education. This contrasts with SCZ patients, who showed both intellectual and educational deficits compared to healthy controls. Since relatives of BD-I patients did not demonstrate superior educational performance, our data suggest that high educational performance may be a distinctive feature of bipolar disorder patients.
وصف الملف: image/pdf; application/pdf
اللغة: English
تدمد: 0033-2917
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4c01abf41e5b9b651523b4f8b34b56
https://dspace.library.uu.nl/handle/1874/333761
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....bb4c01abf41e5b9b651523b4f8b34b56
قاعدة البيانات: OpenAIRE
الوصف
تدمد:00332917