Role of environmental factors in shaping spatial distribution of salmonella enterica Serovar Typhi, Fiji
| العنوان: | Role of environmental factors in shaping spatial distribution of salmonella enterica Serovar Typhi, Fiji |
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| المؤلفون: | Nga Tran Vu Thieu, Kitione Rawalai, Tan Trinh Van, Jerimaia Coriakula, Colleen L. Lau, Conall H. Watson, Jorge Cano, Ruklanthi de Alwis, Mere Taufa, Mike Kama, Birgit Nikolay, Stephen Baker, John H. Lowry, W. John Edmunds, Dung Tran Thi Ngoc, Eric J. Nilles |
| المساهمون: | Baker, Stephen [0000-0003-1308-5755], Apollo - University of Cambridge Repository |
| المصدر: | Emerging Infectious Diseases, Vol 24, Iss 2, Pp 284-293 (2018) Emerging Infectious Diseases |
| مصطلحات موضوعية: | Veterinary medicine, Epidemiology, Cross-sectional study, lcsh:Medicine, Salmonella typhi, Serology, 0302 clinical medicine, Seroepidemiologic Studies, Environmental Microbiology, Cluster Analysis, risk factors, 030212 general & internal medicine, Child, bacteria, Aged, 80 and over, seroprevalence, Middle Aged, Antibodies, Bacterial, 3. Good health, Vaccination, Infectious Diseases, Child, Preschool, Salmonella enterica serovar Typhi, multilevel analysis, typhoid fever, Microbiology (medical), Adult, Adolescent, 030231 tropical medicine, Vi antibodies, Biology, Disease cluster, Peptides, Cyclic, Typhoid fever, Role of Environmental Factors in Shaping Spatial Distribution of Salmonella enterica Serovar Typhi, Fiji, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, flooding, environmental factors, medicine, Seroprevalence, Fiji, Humans, lcsh:RC109-216, Aged, Research, lcsh:R, Infant, Newborn, Infant, Odds ratio, medicine.disease, Cross-Sectional Studies, Vi capsular antigen |
| الوصف: | Fiji recently experienced a sharp increase in reported typhoid fever cases. To investigate geographic distribution and environmental risk factors associated with Salmonella enterica serovar Typhi infection, we conducted a cross-sectional cluster survey with associated serologic testing for Vi capsular antigen-specific antibodies (a marker for exposure to Salmonella Typhi in Fiji in 2013. Hotspots with high seroprevalence of Vi-specific antibodies were identified in northeastern mainland Fiji. Risk for Vi seropositivity increased with increased annual rainfall (odds ratio [OR] 1.26/quintile increase, 95% CI 1.12-1.42), and decreased with increased distance from major rivers and creeks (OR 0.89/km increase, 95% CI 0.80-0.99) and distance to modeled flood-risk areas (OR 0.80/quintile increase, 95% CI 0.69-0.92) after being adjusted for age, typhoid fever vaccination, and home toilet type. Risk for exposure to Salmonella Typhi and its spatial distribution in Fiji are driven by environmental factors. Our findings can directly affect typhoid fever control efforts in Fiji. |
| وصف الملف: | application/pdf |
| تدمد: | 1080-6059 1080-6040 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7bef791ce80af7d780e569e68083ae http://ora.ox.ac.uk/objects/uuid: |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bd7bef791ce80af7d780e569e68083ae |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10806059 10806040 |
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