Impact of laparoscopic antireflux surgery on belching in pediatric GERD patients
| العنوان: | Impact of laparoscopic antireflux surgery on belching in pediatric GERD patients |
|---|---|
| المؤلفون: | Peter D. Siersema, Nicolaas Fedde Rinsma, José M. Conchillo, M. Y. A. van Herwaarden-Lindeboom, D. C. van der Zee, Roderick H. J. Houwen, Cornelius E. J. Sloots, F A Mauritz, L. W. E. van Heurn, Ad A.M. Masclee |
| المساهمون: | Ondersteunend personeel NTM, MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), Surgery, MUMC+: MA Maag Darm Lever (9), RS: NUTRIM - R2 - Gut-liver homeostasis, Interne Geneeskunde, Pediatric Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Surgery |
| المصدر: | Neurogastroenterology and Motility, 28(10), 1525-1532. Wiley Neurogastroenterology and Motility, 28, 10, pp. 1525-32 Neurogastroenterology and Motility, 28, 1525-32 Neurogastroenterology and Motility, 28(10), 1525–1532. Wiley-Blackwell Neurogastroenterology and Motility, 28(10), 1525-1532. Wiley-Blackwell Publishing Ltd Neurogastroenterology and motility, 28(10), 1525-1532. Wiley-Blackwell |
| بيانات النشر: | Wiley, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Impedance–pH monitoring, Esophageal pH Monitoring, Adolescent, pediatrics, Physiology, gastroesophageal reflux disease, laparoscopic fundoplication, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, 0302 clinical medicine, Bloating, belching, gas, Journal Article, Eructation, medicine, Humans, Prospective Studies, Child, Solid content, Antireflux surgery, Endocrine and Autonomic Systems, business.industry, Stomach, Gastroenterology, Reflux, medicine.disease, digestive system diseases, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Anesthesia, Gastroesophageal Reflux, GERD, Female, Laparoscopy, 030211 gastroenterology & hepatology, business, Follow-Up Studies, Cohort study |
| الوصف: | Item does not contain fulltext BACKGROUND: Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pomp inhibitor (PPI)-resistant gastroesophageal reflux disease (GERD). Besides preventing reflux of gastric fluid and solid content, LARS may also impair the ability of the stomach to vent intragastric air (i.e. gastric belching) and induce gas-related complications, such as bloating and/or hyperflatulence. Furthermore, it was previously hypothesized that LARS induces a behavioral type of belching, not originating from the stomach, called supragastric belching. The aim of this study was to objectively evaluate the impact of LARS on gastric (GB) and supragastric belching (SGB) in children with GERD. METHODS: We performed a prospective, Dutch multicenter cohort study including 25 patients (12 males, median age 6 (range 2-18) years) with PPI-resistant GERD who were scheduled for LARS. Twenty-four-hour multichannel intraluminal impedance pH monitoring (MII-pH monitoring) was performed before and 3 months after fundoplication. Impedance pH tracings were analyzed for reflux episodes and GBs and SGBs. KEY RESULTS: LARS reduced acid exposure time from 8.5% (6.0-16.2%) to 0.8% (0.2-2.8%), p < 0.001. The number of GBs also significantly decreased after LARS (59 [43-77] VS 5 [2-12], p < 0.001). The number of air swallows remained unchanged after LARS. SGBs were infrequent before LARS with no change in the number of SGB observed after the procedure. Postoperative belching symptoms were associated with GBs, not with SGBs. CONCLUSION & INFERENCES: LARS significantly reduces the number of GBs in children with GERD, whereas the number of air swallows remains unchanged. Postoperative symptomatic belching is associated with GBs, but not with SGBs. These findings suggest that LARS does not induce the occurrence of SGBs in children, but longer follow-up is required. |
| وصف الملف: | image/pdf; application/pdf |
| تدمد: | 1350-1925 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcce0aecd45b79a8d31304246a7a4a2 https://doi.org/10.1111/nmo.12850 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bdcce0aecd45b79a8d31304246a7a4a2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13501925 |
|---|