Work history and radioprotection practices in relation to cancer incidence and mortality in US radiologic technologists performing nuclear medicine procedures
| العنوان: | Work history and radioprotection practices in relation to cancer incidence and mortality in US radiologic technologists performing nuclear medicine procedures |
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| المؤلفون: | Cari M. Kitahara, Daphne Villoing, Martha S. Linet, Miriam E. Van Dyke, Marie Odile Bernier, Michele M. Doody, Bruce H. Alexander |
| المساهمون: | PSE-SANTE/SESANE/LEPID, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), National Cancer Institute [Bethesda] (NCI-NIH), National Institutes of Health [Bethesda] (NIH), Rollins School of Public Health, DIVISION OF ENVIRONMENTAL HEALTH SCIENCES, University of Minnesota |
| المصدر: | Occupational and Environmental Medicine Occupational and Environmental Medicine, BMJ Publishing Group, 2018, 8 (75), pp.533-561. ⟨10.1136/oemed-2017-104559⟩ |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Employment, Male, Neoplasms, Radiation-Induced, [SDV]Life Sciences [q-bio], Health Personnel, Risk Assessment, Article, 030218 nuclear medicine & medical imaging, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Radiation Protection, Neoplasms, Occupational Exposure, Surveys and Questionnaires, medicine, Humans, Technology, Radiologic, Aged, Cancer mortality, business.industry, Incidence, Public Health, Environmental and Occupational Health, Cancer, Middle Aged, medicine.disease, United States, 3. Good health, Occupational Diseases, Increased risk, Cancer incidence, 030220 oncology & carcinogenesis, Female, Work history, Nuclear Medicine, Cancer risk, business, Nuclear medicine, Procedures and Techniques Utilization, Cohort study |
| الوصف: | IntroductionTechnologists working in nuclear medicine (NM) are exposed to higher radiation doses than most other occupationally exposed populations. The aim of this study was to estimate the risk of cancer in NM technologists in relation to work history, procedures performed and radioprotection practices.MethodsFrom the US Radiologic Technologists cohort study, 72 755 radiologic technologists who completed a 2003–2005 questionnaire were followed for cancer mortality through 31 December 2012 and for cancer incidence through completion of a questionnaire in 2012–2013. Multivariable-adjusted models were used to estimate HRs for total cancer incidence and mortality by history of ever performing NM procedures and frequency of performing specific diagnostic or therapeutic NM procedures and associated radiation protection measures by decade.ResultsDuring follow-up (mean=7.5 years), 960 incident cancers and 425 cancer deaths were reported among the 22 360 technologists who worked with NM procedures. We observed no increased risk of cancer incidence (HR 0.96, 95% CI 0.89 to 1.04) or death (HR 1.05, 95% CI 0.93 to 1.19) among workers who ever performed NM procedures. HRs for cancer incidence but not mortality were higher for technologists who began performing therapeutic procedures in 1960 and later compared with the 1950s. Frequency of performing diagnostic or therapeutic NM procedures and use of radioprotection measures were not consistently associated with cancer risk. No clear associations were observed for specific cancers, but results were based on small numbers.ConclusionCancer incidence and mortality were not associated with NM work history practices, including greater frequency of procedures performed. |
| تدمد: | 1470-7926 1351-0711 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf2702785d85f8e456feb15ba8657c6 https://pubmed.ncbi.nlm.nih.gov/29720482 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bdf2702785d85f8e456feb15ba8657c6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14707926 13510711 |
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