Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy

التفاصيل البيبلوغرافية
العنوان: Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy
المؤلفون: M Worn, Donat R. Spahn, Michael T. Ganter, Mirko Brenni, Martin Brüesch
المساهمون: University of Zurich, Brenni, M
المصدر: Acta anaesthesiologica Scandinavica. 54(1)
سنة النشر: 2009
مصطلحات موضوعية: Male, medicine.medical_specialty, Antifibrinolytic, 10216 Institute of Anesthesiology, medicine.drug_class, 610 Medicine & health, Hemorrhage, Young Adult, Coagulopathy, medicine, case report, Humans, Platelet, Hemostasis, business.industry, Fibrinolysis, Fibrinogen, General Medicine, medicine.disease, Afibrinogenemia, Hyperfibrinolysis, Antifibrinolytic Agents, Surgery, Thrombelastography, Thromboelastometry, Anesthesiology and Pain Medicine, Abdominal trauma, Tranexamic Acid, Anesthesia, Wounds and Injuries, 2703 Anesthesiology and Pain Medicine, business, Packed red blood cells, Tranexamic acid, medicine.drug
الوصف: Transfusion of allogeneic blood products is associated with increased morbidity and mortality. Therefore, strategies for reducing transfusion of these products during trauma management are valuable. We report a case of severe blunt abdominal trauma, successfully treated with antifibrinolytic medication and fibrinogen concentrate. Rotational thromboelastometry (ROTEM) was used to identify hyperfibrinolysis and afibrinogenaemia. In order to achieve haemostasis, over a 3-h period, the patient received a total of 1 g of tranexamic acid, 7 U of packed red blood cells, 16 g of fibrinogen concentrate (Haemocomplettan P), 3500 ml of colloids and 5500 ml of lactated Ringer's solution. Together with surgical measures, this treatment stopped the bleeding and stabilised the patient. There was no transfusion of either fresh-frozen plasma or platelets. The limited need for allogeneic blood products is of particular interest, and clinical studies of the approach used here appear to be warranted.
وصف الملف: Ganter_AAS_2009_24480.pdf - application/pdf
تدمد: 1399-6576
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dd3310b7ec655dbf28f011c01c0d66
https://pubmed.ncbi.nlm.nih.gov/19860752
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....c0dd3310b7ec655dbf28f011c01c0d66
قاعدة البيانات: OpenAIRE