Relative reactivity of HIV-1 polyclonal plasma antibodies directed to V3 and MPER regions suggests immunodominance of V3 over MPER and dependence of high anti-V3 antibody titers on virus persistence
| العنوان: | Relative reactivity of HIV-1 polyclonal plasma antibodies directed to V3 and MPER regions suggests immunodominance of V3 over MPER and dependence of high anti-V3 antibody titers on virus persistence |
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| المؤلفون: | R.M. Pandey, Rajesh Kalra, SS Prakash, Manju Bala, Alok Choudhary, Raiees Andrabi, Kalpana Luthra |
| المصدر: | Archives of Virology. 156 |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Adult, Male, Amino Acid Motifs, HIV Infections, Immunodominance, HIV Antibodies, HIV Envelope Protein gp120, Gp41, Neutralization, Virus, Young Adult, Virology, Humans, biology, Antibody titer, General Medicine, Middle Aged, Viral Load, HIV Envelope Protein gp41, Titer, Polyclonal antibodies, Immunology, HIV-1, biology.protein, Female, Antibody, Follow-Up Studies |
| الوصف: | Antibodies to two crucial regions, the third variable loop (V3) of gp120 and the membrane-proximal external region (MPER) of gp41 are important for HIV-1 neutralization. We here evaluated the relative binding of polyclonal plasma antibodies from 99 HIV-1-infected individuals from India to the consensus–C V3 and MPER peptides and observed immunodominance of V3 over MPER (p |
| تدمد: | 1432-8798 0304-8608 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b416771516d4eec71393e3c4f06840 https://doi.org/10.1007/s00705-011-1053-5 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c3b416771516d4eec71393e3c4f06840 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14328798 03048608 |
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