Human African trypanosomiasis in two historical foci of the estuaire province, gabon: A case report
| العنوان: | Human African trypanosomiasis in two historical foci of the estuaire province, gabon: A case report |
|---|---|
| المؤلفون: | Berthe Amélie Iroungou, Larson Boundenga, Gael Darren Maganga, Laurette Guignali Mangouka, Jean Raymond Nzenze, Berthold Bivigou-Mboumba |
| المصدر: | SAGE Open Medical Case Reports, Vol 8 (2020) SAGE Open Medical Case Reports |
| بيانات النشر: | SAGE Publishing, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Trypanosoma brucei gambiense, Noya, 030231 tropical medicine, Case Report, Disease, 03 medical and health sciences, 0302 clinical medicine, Eflornithine, parasitic diseases, medicine, African trypanosomiasis, Komo, Nifurtimox, 030304 developmental biology, 0303 health sciences, lcsh:R5-920, biology, business.industry, Human African trypanosomiasis, General Medicine, biology.organism_classification, medicine.disease, Virology, northwestern Gabon, Infectious disease (medical specialty), Trypanosoma, Protozoa, business, lcsh:Medicine (General), medicine.drug |
| الوصف: | Human African Trypanosomiasis (HAT) is an infectious disease due to a protozoa parasite of the Trypanosoma genus. In West and Central Africa, this disease is caused by the subspecies Trypanosoma brucei gambiense. Several foci of this disease are currently active and causing the death of hundreds of people in endemic areas. In this article, we report two cases of gambiense HAT in one Indonesian and one Gabonese men in two historical foci of Gabon in 2019. Both patients had fever with temperatures above 38°C, an altered state of consciousness, cachexia, and multiple dermabrasions on the abdomen related to scratching lesions. The diagnostic revealed second-stage infection of both patients with T. b. gambiense; this result was confirmed by a polymerase chain reaction assay. Despite treatment with a combination of eflornithine and nifurtimox, as recommended by the World Health Organization for late-stage T. b. gambiense HAT, one of the two patients died. Thus, these cases highlight the importance of early HAT diagnosis and prompt patient care to fight effectively against this disease. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3df4fb2bdb5dadec9295a3544335015 https://doaj.org/article/2992736ab584401490080beec95fb64b |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c3df4fb2bdb5dadec9295a3544335015 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |