FEATURES OF ENDOMETRIAL STROMA DECIDUALIZATION IN EARLY PREGNANCY LOSS

التفاصيل البيبلوغرافية
العنوان: FEATURES OF ENDOMETRIAL STROMA DECIDUALIZATION IN EARLY PREGNANCY LOSS
المؤلفون: Luchko E. V., Shtabinskaya T. T., Zubritsky M. G., Basinskiy V. A.
المصدر: Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, Vol 16, Iss 6, Pp 702-705 (2018)
بيانات النشر: Grodno State Medical University, 2018.
سنة النشر: 2018
مصطلحات موضوعية: medicine.drug_class, business.industry, miscarriage, lcsh:R, Decidualization, desmin, lcsh:Medicine, Normal pregnancy, Monoclonal antibody, medicine.disease, Miscarriage, Andrology, decidualization, medicine, Immunohistochemistry, Decidual cells, Desmin, Receptor, business
الوصف: Background. Decidualization of the endometrial stroma is a multistage process. The immunohistochemical marker of differentiation of decidual cells is desmin. Purpose of the study. The estimation of the prognostic significance of the level of desmin expression in decidual tissue in early miscarriage. Material and methods: Clinico-morphological analysis of 102 cases of miscarriage revealed in women of the Grodno region in 2005 was carried out. Immunohistochemical studies were performed using murine monoclonal antibodies to Desmin receptors (Dako-Cytomation, M076001). Results: The level of desmin expression in the endometrial stroma of patients with miscarriage is significantly higher than in normal pregnancy (p = 0.002). Conclusions: At a positivity level of desmin expression in the endometrial stroma greater than 0.004 it is possible to predict miscarriage with a sensitivity of 100% and a specificity of 100%.
اللغة: Belarusian
تدمد: 2413-0109
2221-8785
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd50207ecfa80187567b0b18910cc30
http://journal-grsmu.by/index.php/ojs/article/view/2347/2143
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....ccd50207ecfa80187567b0b18910cc30
قاعدة البيانات: OpenAIRE