Immunogenicity of Fowlpox Virus Expressing the Avian Influenza Virus H5 Gene (TROVAC AIV-H5) in Cats
| العنوان: | Immunogenicity of Fowlpox Virus Expressing the Avian Influenza Virus H5 Gene (TROVAC AIV-H5) in Cats |
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| المؤلفون: | David E. Swayne, Amy Robles, Robert Nordgren, Kemal Karaca, Michel Bublot, Deborah A. Grosenbaugh, Erica Spackman |
| المصدر: | Clinical and Vaccine Immunology. 12:1340-1342 |
| بيانات النشر: | American Society for Microbiology, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Microbiology (medical), viruses, Clinical Biochemistry, Immunology, Hemagglutinin Glycoproteins, Influenza Virus, Biology, Antibodies, Viral, Cat Diseases, medicine.disease_cause, H5N1 genetic structure, Virus, Microbiology, Virus antigen, Influenza, Human, medicine, Animals, Humans, Immunology and Allergy, Fowlpox virus, Hemagglutination assay, Organisms, Genetically Modified, Immunogenicity, virus diseases, Hemagglutination Inhibition Tests, Virology, Influenza A virus subtype H5N1, Vaccination, Influenza Vaccines, Cats, Microbial Immunology |
| الوصف: | Vaccination of cats with fowlpox virus expressing the avian influenza (AI) virus H5 hemagglutinin gene (TROVAC AI) resulted in detectable hemagglutination inhibition (HI) antibody responses to the homologous A/Turkey/Ireland/1378/83 (H5N8) (A/tky/Ire/83) AI virus antigen. The HI antibody responses to heterologous A/Chicken/Indonesia/7/03 (H5N1) (A/ck/Indonesia/03) AI virus antigen were also detected in all vaccinated cats, but only after booster vaccinations. The vaccine described in this study and other poxvirus-vectored vaccines may be of value for the prophylaxis of AI virus-associated morbidity and mortality in mammals. |
| تدمد: | 1556-679X 1556-6811 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1affb99db9973a8d91953571b574e60 https://doi.org/10.1128/cdli.12.11.1340-1342.2005 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....d1affb99db9973a8d91953571b574e60 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1556679X 15566811 |
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