Cardiovascular Effects of High-Frequency Magnetic Seizure Therapy Compared With Electroconvulsive Therapy
| العنوان: | Cardiovascular Effects of High-Frequency Magnetic Seizure Therapy Compared With Electroconvulsive Therapy |
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| المؤلفون: | Jun-Yan, Zhang, Han, Wu, Li-Na, Jia, Wei, Jiang, Jiong, Luo, Yi, Liu, Qi, Gao, Yan-Ping, Ren, Xin, Ma, Yi-Lang, Tang, William M, McDonald |
| المصدر: | The Journal of ECT. 38:185-191 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Psychiatry and Mental health, Seizures, Neuroscience (miscellaneous), Humans, Anesthesia, Electroencephalography, Electroconvulsive Therapy |
| الوصف: | Magnetic seizure therapy (MST) is a novel convulsive therapy that has been shown to have antidepressant efficacy comparable to electroconvulsive therapy (ECT) with fewer cognitive side effects. However, the cardiovascular (CVS) effects of high frequency MST in comparison to ECT have not been investigated.Forty-five patients with depression received 6 treatment sessions of 100 Hz MST versus 6 bifrontal ECT treatments in a nonrandomized comparative clinical design. Data on CVS function including heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and rate pressure product (RPP) were collected at baseline (T0), after the induction of anesthesia but before the electrical stimulation (T1), during convulsion (T2), 2 minutes after cessation of motor seizure (T3), 5 minutes after cessation of motor seizure (T4), and 10 minutes after cessation of motor seizure (T5). Comparisons were made with baseline data and between MST and ECT groups.There were statistically significant elevations in the maximum HR, SBP, DBP, and RPP in patients receiving ECT compared with MST both in the initial and sixth treatments (all P0.05). Particularly, at T2, the ECT group had significantly higher HR, SBP, DBP, and RPP than those in MST group both in initial and sixth treatment (all P0.001). At the sixth treatment, the ECT group had significantly higher SBP, DBP, and RPP during the treatment than in the MST group (all P0.001).The anesthetic choices for this study may limit the generalizability of our findings. The sample size was relatively small.Compared with ECT, high-frequency MST has fewer CVS side effects and may be a safer option for depression patients with CVS disorders. |
| تدمد: | 1533-4112 1095-0680 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e0cd78f80365198a6337a210fc11ae https://doi.org/10.1097/yct.0000000000000833 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e1e0cd78f80365198a6337a210fc11ae |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15334112 10950680 |
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