High-Sensitivity C Reactive Protein: Associations with Cardiovascular Risk Factors and Tracking in Female Adolescents and Young Adults
| العنوان: | High-Sensitivity C Reactive Protein: Associations with Cardiovascular Risk Factors and Tracking in Female Adolescents and Young Adults |
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| المؤلفون: | Charles J. Glueck, John A. Morrison, Ping Wang, Paul S. Horn, Stephen R. Daniels, Davis Stroop |
| المصدر: | ISRN Pediatrics |
| بيانات النشر: | Hindawi Limited, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pediatrics, Waist, Article Subject, biology, Triglyceride, business.industry, Cholesterol, C-reactive protein, nutritional and metabolic diseases, Anthropometry, Stepwise regression, chemistry.chemical_compound, chemistry, Internal medicine, biology.protein, Medicine, cardiovascular diseases, Young adult, business, Prospective cohort study, Research Article |
| الوصف: | Objective. We assessed adolescent anthropometry, lipids, insulin, glucose, and blood pressures to identify factors associated with high-sensitivity C-reactive protein (hsCRP) and its tracking in young adults. Methods. Ten-year prospective study of 589 schoolgirls, 321 black, 268 white. Results. HsCRP did not differ (P>.08) by race or oral contraceptive use. HsCRP tracked from age 16 to 25 (r=0.77), 16 to 26 (r=0.50), 24 to 26 (r=0.66), and 25 to 26 (r=0.71), all P≤.02. By stepwise regression, at age 16, waist circumference accounted for 44.8% of hsCRP variance; BMI accounted for 33.1%, 34.4%, and 31.1% at ages 24, 25, and 26, P<.0001 for all. Changes in cholesterol and BMI were associated with change in hsCRP from age 24–26 (partial R2=12.3% P<.0001, 6.6% P=.0012). Changes in BMI and triglyceride (partial R2=8.5% P=.0001, 3.3%, P=.0045) were associated with change in hsCRP from age 25 to 26. Conclusions. HsCRP tracks from age 16 to 26, with BMI, waist circumference, and cholesterol as major determinants. |
| وصف الملف: | text/xhtml |
| تدمد: | 2090-4703 2090-469X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d1d0e7ad395d3a3e1546e3621cfb21 https://doi.org/10.5402/2011/707206 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e2d1d0e7ad395d3a3e1546e3621cfb21 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20904703 2090469X |
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