Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study
| العنوان: | Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study |
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| المؤلفون: | Rosalinde A L Smits, Stella Trompet, Carolien M J van der Linden, Jessica M van der Bol, Steffy W M Jansen, Harmke A Polinder-Bos, Hanna C Willems, Dennis G Barten, Laura C Blomaard, Mark G J de Boer, Floor J A van Deudekom, Jacobien L J Ellerbroek, Jan Festen, Esther M M van de Glind, Linda M Kampschreur, Ouafae Karimi, Bart Kroon, Marc G J A van Lanen, Jacinta A Lucke, Huub A A M Maas, Francesco U S Mattace-Raso, Barbara C van Munster, Lisette Reijerse, Sarah H M Robben, Rikje Ruiter, Henrike J Schouten, Petra E Spies, Anna Wassenburg, Marjolein A Wijngaarden, Simon P Mooijaart |
| المساهمون: | Geriatrics, APH - Aging & Later Life, AMS - Amsterdam Movement Sciences, AMS - Ageing & Vitality, Value, Affordability and Sustainability (VALUE), Molecular Neuroscience and Ageing Research (MOLAR), Internal Medicine |
| المصدر: | Age and Ageing, 51(3). OXFORD UNIV PRESS Age and ageing, 51(3):afac048. Oxford University Press Age and Ageing, 51(3):afac048. Oxford University Press |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Male, Aging, SARS-CoV-2, MORTALITY, SCREENING TOOL, COVID-19, second pandemic wave, General Medicine, frailty, MALNUTRITION, Humans, Female, Geriatrics and Gerontology, Pandemics, Aged, Netherlands, Retrospective Studies, in-hospital mortality |
| الوصف: | Background as the coronavirus disease of 2019 (COVID-19) pandemic progressed diagnostics and treatment changed. Objective to investigate differences in characteristics, disease presentation and outcomes of older hospitalised COVID-19 patients between the first and second pandemic wave in The Netherlands. Methods this was a multicentre retrospective cohort study in 16 hospitals in The Netherlands including patients aged ≥ 70 years, hospitalised for COVID-19 in Spring 2020 (first wave) and Autumn 2020 (second wave). Data included Charlson comorbidity index (CCI), disease severity and Clinical Frailty Scale (CFS). Main outcome was in-hospital mortality. Results a total of 1,376 patients in the first wave (median age 78 years, 60% male) and 946 patients in the second wave (median age 79 years, 61% male) were included. There was no relevant difference in presence of comorbidity (median CCI 2) or frailty (median CFS 4). Patients in the second wave were admitted earlier in the disease course (median 6 versus 7 symptomatic days; P Conclusions compared with older patients hospitalised in the first COVID-19 wave, patients in the second wave had lower in-hospital mortality, independent of risk factors for mortality. The better prognosis likely reflects earlier diagnosis, the effect of improvement in treatment and is relevant for future guidelines and treatment decisions. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0002-0729 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c12d37e6776b7812a56e0552ee51da http://hdl.handle.net/1887/3303605 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e5c12d37e6776b7812a56e0552ee51da |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00020729 |
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