التفاصيل البيبلوغرافية
| العنوان: |
Transurethral prostate magnetic resonance elastography: Prospective imaging requirements |
| المؤلفون: |
Rajiv Chopra, Donald B. Plewes, Arvin Arani |
| المصدر: |
Magnetic Resonance in Medicine. 65:340-349 |
| بيانات النشر: |
Wiley, 2010. |
| سنة النشر: |
2010 |
| مصطلحات موضوعية: |
Male, medicine.medical_specialty, Shear waves, Materials science, Vibration, Prostate cancer, Dogs, Prostate, medicine, Animals, Radiology, Nuclear Medicine and imaging, Penetration depth, Phantoms, Imaging, Stiffness, equipment and supplies, medicine.disease, Elasticity, Magnetic resonance elastography, medicine.anatomical_structure, Attenuation coefficient, Elasticity Imaging Techniques, Radiology, medicine.symptom, Actuator, Biomedical engineering |
| الوصف: |
Tissue stiffness is known to undergo alterations when affected by prostate cancer and may serve as an indicator of the disease. Stiffness measurements can be made with magnetic resonance elastography performed using a transurethral actuator to generate shear waves in the prostate gland. The goal of this study was to help determine the imaging requirements of transurethral magnetic resonance elastography and to evaluate whether the spatial and stiffness resolution of this technique overlapped with the requirements for prostate cancer detection. Through the use of prostate-mimicking gelatin phantoms, frequencies of at least 400 Hz were necessary to obtain accurate stiffness measurements of 10 mm diameter inclusions, but the detection of inclusions with diameters as small as 4.75 mm was possible at 200 Hz. The shear wave attenuation coefficient was measured in vivo in the canine prostate gland, and was used to predict the detectable penetration depth of shear waves in prostate tissue. These results suggested that frequencies below 200 Hz could propagate to the prostate boundary with a signal to noise ratio (SNR) of 60 and an actuator capable of producing 60 μm displacements. These requirements are achievable with current imaging and actuator technologies, and motivate further investigation of magnetic resonance elastography for the targeting of prostate cancer. Magn Reson Med, 2011. © 2010 Wiley-Liss, Inc. |
| تدمد: |
0740-3194 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6620259e364c29e1f3d35f3ea8cffb1
https://doi.org/10.1002/mrm.22633 |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.doi.dedup.....e6620259e364c29e1f3d35f3ea8cffb1 |
| قاعدة البيانات: |
OpenAIRE |
