Prediction of left ventricular ejection fraction 6 months after surgical correction of organic mitral regurgitation: the value of exercise echocardiography and deformation imaging
| العنوان: | Prediction of left ventricular ejection fraction 6 months after surgical correction of organic mitral regurgitation: the value of exercise echocardiography and deformation imaging |
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| المؤلفون: | Alain Leguerrier, Anne Brunet, Hervé Corbineau, Christophe Thebault, Erwan Donal, M. Laurent, Philippe Mabo, Sophie Mascle |
| المساهمون: | Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], CIC-IT Rennes, Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de chirurgie thoracique cardiaque et vasculaire [Rennes] = Thoracic and Cardiovascular Surgery [Rennes], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| المصدر: | European Heart Journal-Cardiovascular Imaging European Heart Journal-Cardiovascular Imaging, 2012, 13 (11), pp.922-30. ⟨10.1093/ehjci/jes068⟩ European Heart Journal-Cardiovascular Imaging, Oxford UP, 2012, 13 (11), pp.922-30. ⟨10.1093/ehjci/jes068⟩ |
| بيانات النشر: | HAL CCSD, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, Global longitudinal strain, MESH: Mitral Valve Insufficiency, Time Factors, Statistics as Topic, Hemodynamics, 030204 cardiovascular system & hematology, MESH: Stroke Volume, Ventricular Function, Left, MESH: Ventricular Function, Left, Coronary artery disease, 0302 clinical medicine, Postoperative Complications, MESH: Postoperative Complications, Health Status Indicators, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Ejection fraction, MESH: Middle Aged, Left ventricular function, Mitral Valve Insufficiency, General Medicine, Stroke volume, Middle Aged, Prognosis, MESH: Predictive Value of Tests, Predictive value of tests, Cardiology, Disease Progression, cardiovascular system, Female, MESH: Disease Progression, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, MESH: Hemodynamics, Preoperative care, MESH: Prognosis, 03 medical and health sciences, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Predictive Value of Tests, Internal medicine, MESH: Health Status Indicators, medicine, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, MESH: Statistics as Topic, Mitral regurgitation, MESH: Humans, business.industry, MESH: Time Factors, Stroke Volume, Ultrasonography, Doppler, medicine.disease, MESH: Prospective Studies, MESH: Male, Exercise Test, MESH: Ultrasonography, Doppler, Exercise stress echocardiography, business, MESH: Exercise Test, MESH: Female |
| الوصف: | International audience; AIMS: Left ventricular (LV) end-systolic diameter and LV ejection fraction (LVEF) are correlated with postoperative LVEF and prognosis in patients with organic mitral regurgitation (MR). However, in some patients, the LVEF does not return to normal 6 months postoperatively, despite normal preoperative diameters. Thus, our study aimed to evaluate whether preoperative LV strain values assessed by echocardiography at rest and during exercise were predictors of postoperative LVEF at 6-month follow-up in patients undergoing surgery for severe organic MR. METHODS AND RESULTS: In total, 88 patients with severe organic MR (mean age 62.6 ± 1.4 years) were prospectively recruited. All patients underwent an echocardiogram at rest and submaximal exercise (110 ± 10 bpm) prior to surgery and then at rest 6 months after surgery. Exclusion criteria were significant coronary artery disease, other organic valvular diseases, uncontrolled arrhythmia, and haemodynamic instability. Among the 88 patients, 77 had complete data sets with rest and exercise echocardiograms and underwent isolated mitral valve surgery (repaired, n= 72). Global longitudinal strain (GLS) at rest (R= -0.42, P= 0.011) and during exercise (R= -0.36, P= 0.034) correlated with postoperative LVEF. When normalized for LV end-systolic diameter, GLS during exercise was more closely correlated with postoperative LVEF and was its best predictor based on a multivariate linear regression model. At a cut-off of -5.7%/cm, sensitivity was 0.83, specificity 0.70, negative predictive value 0.64, and positive predictive value 0.86 for predicting a 6-month postoperative LVEF of |
| اللغة: | English |
| تدمد: | 2047-2404 2047-2412 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97ef6396eb9a12f2fdaa805c127c363 https://hal.science/hal-00904242 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e97ef6396eb9a12f2fdaa805c127c363 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20472404 20472412 |
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