Differentiating Dengue from COVID-19: Comparison of Cases in Colombia
| العنوان: | Differentiating Dengue from COVID-19: Comparison of Cases in Colombia |
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| المؤلفون: | Olga L. Agudelo-Rojas, Diana Marcela Martínez-Ruiz, Luis Gabriel Parra-Lara, Fernando Rosso |
| المصدر: | The American Journal of Tropical Medicine and Hygiene |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Coronavirus disease 2019 (COVID-19), Neutrophils, Disease, Single Center, Dengue fever, Dengue, Diagnosis, Differential, Young Adult, Virology, Internal medicine, Humans, Medicine, Lymphocytes, biology, SARS-CoV-2, business.industry, COVID-19, Articles, Emergency department, Middle Aged, medicine.disease, Cross-Sectional Studies, Infectious Diseases, Alanine transaminase, Sample size determination, biology.protein, Absolute neutrophil count, Female, Parasitology, business |
| الوصف: | The differentiation between dengue and COVID-19 diagnoses is a challenge in tropical regions because of the similarity of symptoms and limited access to specific diagnostic tests for each disease. The objective of this study was to describe the initial symptoms and laboratory test values of patients who presented to the emergency department with dengue or COVID-19. A cross-sectional study was performed in a single center in Cali, Colombia. The inclusion criteria were patients with a diagnosis of dengue or COVID-19 who were older than 14 years of age. All patients experienced fever or other symptoms for fewer than 10 days. Linear regression was performed to evaluate the differences in the neutrophil-lymphocyte ratio (NLR) between patients diagnosed with COVID-19 and dengue, and was adjusted for sex and age group (≤ 31 and > 31 years). The sample size was calculated to test the hypothesis that the median NLR in COVID-19 patients is higher than that in dengue patients. A P value < 0.05 was considered statistically significant for all analyses. A total of 93 patients were included: 70 with dengue and 23 with COVID-19. Dengue patients were younger than COVID-19 patients. There were significant differences between dengue and COVID-19 patients regarding platelet count (P < 0.01), neutrophil count (P < 0.01), NLR (P < 0.01), and abnormal alanine transaminase (ALT) (P = 0.03). The NLR was significantly higher in COVID-19 patients than in dengue patients (P < 0.01). In conclusion, during the first week of symptoms, absolute neutrophil count, NLR, and platelet count could help guide the initial differential approach between dengue and COVID-19. These findings could be useful in geographical areas with a lack of resources. |
| تدمد: | 1476-1645 0002-9637 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1aae7440e0c394afb127ff5175cde9 https://doi.org/10.4269/ajtmh.20-0912 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....eb1aae7440e0c394afb127ff5175cde9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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