The changing histological pattern of gastric polyps in an ethnically heterogeneous population
| العنوان: | The changing histological pattern of gastric polyps in an ethnically heterogeneous population |
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| المؤلفون: | Asaf Peretz, Orit Pappo, Elliot Turvall, Dan M. Livovsky, Tal Fuchs, Zvi Ackerman |
| المصدر: | Scandinavian Journal of Gastroenterology. 47:907-913 |
| بيانات النشر: | Informa UK Limited, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, medicine.drug_class, Population, Proton-pump inhibitor, digestive system, Gastroenterology, Endoscopy, Gastrointestinal, Helicobacter Infections, Polyps, Sex Factors, Stomach Neoplasms, Internal medicine, Confidence Intervals, Odds Ratio, Prevalence, otorhinolaryngologic diseases, medicine, Humans, Israel, education, Pathological, Aged, Retrospective Studies, Aged, 80 and over, education.field_of_study, Chi-Square Distribution, Helicobacter pylori, biology, business.industry, Incidence, Proton Pump Inhibitors, Middle Aged, biology.organism_classification, digestive system diseases, Fundic Gland Polyp, Hyperplastic Polyp, Gastric Polyp, Gastritis, Jews, Etiology, Female, business |
| الوصف: | Variation in the prevalence of various types of gastric polyps worldwide may reflect different etiologies. Here, the authors report the dynamic changes in histological distribution of gastric polyps over time and by ethnicity for individuals who underwent gastroscopies between 1994 and 2009 at two hospitals in Jerusalem, Israel. During this time period, the proportion of patients receiving proton pump inhibitors (PPIs) increased while the proportion of patients infected with Helicobacter pylori (H. pylori) decreased.Pathological reports of biopsies from 50,071 consecutive gastroscopies were reviewed.Gastric polyps were detected in 727 individuals. The yearly prevalence of gastric polyps was ≤ 1% between 1994 and 2001 and ≥ 2% from 2004 to 2009, of which overall 66% were hyperplastic polyps and 23% fundic gland polyps (FGPs). FGPs were diagnosed exclusively in the Jewish population. From 2001 to 2004, an increase in the absolute number of newly discovered hyperplastic and FGPs per year was observed. However from 2005, a divergent trend of changes was observed: While the proportion of patients with hyperplastic polyps dropped from 0.72 during the 2001-2004 period to 0.62 during the 2005-2009 period (p = 0.02), the proportion of patients with FGPs at these time periods increased from 0.16 to 0.33 (p = 0.0001).The yearly prevalence of gastric polyps in Jerusalem has recently doubled. This occurred mainly due to the increasing prevalence of FGPs. The changing epidemiology of gastric polyps is probably related to the interaction between genetic factors and fluctuating environmental factors like H. pylori infection rates and exposure to PPIs. |
| تدمد: | 1502-7708 0036-5521 2001-2004 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94261b3c7cb92445692d5d6b6fda3af https://doi.org/10.3109/00365521.2012.682091 |
| رقم الأكسشن: | edsair.doi.dedup.....f94261b3c7cb92445692d5d6b6fda3af |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 15027708 00365521 20012004 |
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