Fatal haemopericardium and gastrointestinal haemorrhage due to possible interaction of cranberry juice with warfarin
العنوان: | Fatal haemopericardium and gastrointestinal haemorrhage due to possible interaction of cranberry juice with warfarin |
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المؤلفون: | A. Beddall, A.P. Griffiths, S. Pegler |
المصدر: | The journal of the Royal Society for the Promotion of Health. 128(6) |
سنة النشر: | 2008 |
مصطلحات موضوعية: | Male, medicine.medical_specialty, Fatal outcome, Gastroenterology, Pericardial Effusion, Beverages, Food-Drug Interactions, food, Fatal Outcome, Internal medicine, Medicine, Potency, Humans, heterocyclic compounds, Drug reaction, food.beverage, Aged, Flavonoids, business.industry, CRANBERRY JUICE, Public Health, Environmental and Occupational Health, Warfarin, food and beverages, Anticoagulants, Gastrointestinal haemorrhage, Surgery, Vaccinium macrocarpon, business, Gastrointestinal Hemorrhage, medicine.drug, Phytotherapy |
الوصف: | We report a case of fatal internal haemorrhage in an elderly man who consumed only cranberry juice for two weeks while maintaining his usual dosage of warfarin. We propose that naturally occurring compounds such as flavonoids, which are present in fruit juices, may increase the potency of warfarin by competing for the enzymes that normally inactivate warfarin. While traditionally regarded as foodstuffs, consumption of fruit juices should be considered when patients develop adverse drug reactions. |
تدمد: | 1466-4240 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe431aabebd76328b3be266103babe29 https://pubmed.ncbi.nlm.nih.gov/19058474 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....fe431aabebd76328b3be266103babe29 |
قاعدة البيانات: | OpenAIRE |
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