Fatal haemopericardium and gastrointestinal haemorrhage due to possible interaction of cranberry juice with warfarin

التفاصيل البيبلوغرافية
العنوان: Fatal haemopericardium and gastrointestinal haemorrhage due to possible interaction of cranberry juice with warfarin
المؤلفون: A. Beddall, A.P. Griffiths, S. Pegler
المصدر: The journal of the Royal Society for the Promotion of Health. 128(6)
سنة النشر: 2008
مصطلحات موضوعية: Male, medicine.medical_specialty, Fatal outcome, Gastroenterology, Pericardial Effusion, Beverages, Food-Drug Interactions, food, Fatal Outcome, Internal medicine, Medicine, Potency, Humans, heterocyclic compounds, Drug reaction, food.beverage, Aged, Flavonoids, business.industry, CRANBERRY JUICE, Public Health, Environmental and Occupational Health, Warfarin, food and beverages, Anticoagulants, Gastrointestinal haemorrhage, Surgery, Vaccinium macrocarpon, business, Gastrointestinal Hemorrhage, medicine.drug, Phytotherapy
الوصف: We report a case of fatal internal haemorrhage in an elderly man who consumed only cranberry juice for two weeks while maintaining his usual dosage of warfarin. We propose that naturally occurring compounds such as flavonoids, which are present in fruit juices, may increase the potency of warfarin by competing for the enzymes that normally inactivate warfarin. While traditionally regarded as foodstuffs, consumption of fruit juices should be considered when patients develop adverse drug reactions.
تدمد: 1466-4240
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe431aabebd76328b3be266103babe29
https://pubmed.ncbi.nlm.nih.gov/19058474
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....fe431aabebd76328b3be266103babe29
قاعدة البيانات: OpenAIRE