Advances in single particle tracking in living cells

التفاصيل البيبلوغرافية
العنوان: Advances in single particle tracking in living cells
المؤلفون: Wang, DJ, Di, XJ, Wang, BM, Wang, F, Guo, ZY, Jin, DY
سنة النشر: 2018
الوصف: © 2018, China Science Publishing & Media LTD. All right reserved. Single particle tracking(SPT) technique locates and tracks individual fluorescent or scattering particles within a cell with the help of microscope system. Based on the ability of real-time monitoring of the complex and highly dynamic changes in tissue structure within living cells and the ability to provide dynamic relationships between structure and function, SPT has important applications in cell biology. In this review,the mechanism of SPT and its application on cells are summarized. Firstly, the dynamics of SPT are introduced, including single particle localization, trajectory reconstruction and analysis. Then the optical materials and instruments that SPT technology focuses on at the present stage are described. Finally, the application of SPT in cell membrane, intracellular signaling pathway, molecular transport mechanism, genetic information expression, and viral infection mechanism are proposed. In addition, the advance of SPT technology are prospected in this paper.
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______363::2c5d3588e2d0a212471cc5f8cd099f6c
https://hdl.handle.net/10453/134025
حقوق: OPEN
رقم الأكسشن: edsair.od.......363..2c5d3588e2d0a212471cc5f8cd099f6c
قاعدة البيانات: OpenAIRE