Regulation of ISWI-family of chromatin remodelling Complexes

التفاصيل البيبلوغرافية
العنوان: Regulation of ISWI-family of chromatin remodelling Complexes
المؤلفون: Toto M, D'Angelo G, CORONA, Davide
المساهمون: Toto M, D'Angelo G, Corona D
بيانات النشر: Springer Berlin Heidelberg, 2013.
سنة النشر: 2013
مصطلحات موضوعية: ISWI, Chromatin Remodeling, Regulation
الوصف: The packaging of DNA into chromatin facilitates the storage of the genetic information within the nucleus but prevents the access to the underlying sequences. The evolutionarily conserved ISWI family of ATP-dependent chromatin remodelling complexes provide one of the regulatory mechanisms that eukaryotic cells have evolved to induce structural changes to chromatin. All ISWI-containing complexes use the energy derived from ATP hydrolysis in order to rearrange nucleosomes on chromatin to carry specific nuclear reactions. The combination of associated proteins with the ATPase subunit as well as specific histone modifications specialize the nuclear function of each ISWI-containing complex. Here we review the many way through which ISWI enzymatic activity can be modulated and regulated in the nucleus of eukaryotic cells.
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3658::4fcd2285ac670314687d7d9112bf18db
http://hdl.handle.net/10447/75309
حقوق: OPEN
رقم الأكسشن: edsair.od......3658..4fcd2285ac670314687d7d9112bf18db
قاعدة البيانات: OpenAIRE