Liquid chromatographic determination of propranolol hydrochloride in various dosage forms
| العنوان: | Liquid chromatographic determination of propranolol hydrochloride in various dosage forms |
|---|---|
| المؤلفون: | C S, Olsen, H S, Scroggins |
| المصدر: | Journal - Association of Official Analytical Chemists. 71(4) |
| سنة النشر: | 1988 |
| مصطلحات موضوعية: | Solutions, Spectrophotometry, Ultraviolet, Propranolol, Chromatography, Liquid, Tablets |
| الوصف: | A simple and rapid liquid chromatographic method is described for the determination of propranolol hydrochloride in pharmaceutical preparations. The separation was achieved on a reverse-phase octylsilane (C8) column by using a mobile phase composed of a mixture of 0.5 g dodecyl sodium sulfate in 18 mL (0.15 M) H3PO4 plus 90 mL methanol, 90 mL acetonitrile, and 52 mL water. Detector response was linear for 0.03-3.1 mg/mL of propranolol. Recoveries from synthetic mixtures ranged from 99.6 to 101.7%. The results obtained by the proposed method were similar to those obtained by the USP XXI method. |
| تدمد: | 0004-5756 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid________::b64942c315e8f3c086d4c0820b65a635 https://pubmed.ncbi.nlm.nih.gov/3417595 |
| رقم الأكسشن: | edsair.pmid..........b64942c315e8f3c086d4c0820b65a635 |
| قاعدة البيانات: | OpenAIRE |
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