تقرير
Detrended Fluctuation Analysis of Systolic Blood Pressure Control Loop
العنوان: | Detrended Fluctuation Analysis of Systolic Blood Pressure Control Loop |
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المؤلفون: | Galhardo, C. E. C., Penna, T. J. P., de Menezes, M. Argollo, Soares, P. P. S. |
سنة النشر: | 2009 |
المجموعة: | Condensed Matter Physics (Other) Quantitative Biology |
مصطلحات موضوعية: | Physics - Biological Physics, Condensed Matter - Statistical Mechanics, Quantitative Biology - Tissues and Organs |
الوصف: | We use detrended fluctuation analysis (DFA) to study the dynamics of blood pressure oscillations and its feedback control in rats by analyzing systolic pressure time series before and after a surgical procedure that interrupts its control loop. We found, for each situation, a crossover between two scaling regions characterized by exponents that reflect the nature of the feedback control and its range of operation. In addition, we found evidences of adaptation in the dynamics of blood pressure regulation a few days after surgical disruption of its main feedback circuit. Based on the paradigm of antagonistic, bipartite (vagal and sympathetic) action of the central nerve system, we propose a simple model for pressure homeostasis as the balance between two nonlinear opposing forces, successfully reproducing the crossover observed in the DFA of actual pressure signals. |
نوع الوثيقة: | Working Paper |
DOI: | 10.1088/1367-2630/11/10/103005 |
URL الوصول: | http://arxiv.org/abs/0908.3614 |
رقم الأكسشن: | edsarx.0908.3614 |
قاعدة البيانات: | arXiv |
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